Detailed information of TA system TA294174

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2038650..2038847
• Replicon: chromosome
• Accession: NZ_LT992466
• Organism: Staphylococcus aureus isolate 4_LA_208

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: DXE30_RS10375
• Protein ID: WP_000623369.1
• Coordinates: 2038740..2038847 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF3
Locus tag	-
Coordinates	2038650..2038687 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DXE30_RS10340	2033751..2034107	+	357	WP_000766009.1	DoxX family protein	-
DXE30_RS10345	2034196..2034384	-	189	WP_157958947.1	poly(glycerol-phosphate) alpha-glucosyltransferase	-
DXE30_RS10350	2034474..2034764	+	291	WP_001796515.1	hypothetical protein	-
DXE30_RS10355	2034852..2035493	-	642	WP_000571192.1	ABC transporter ATP-binding protein	-
DXE30_RS10360	2035490..2035810	-	321	WP_000668623.1	YxeA family protein	-
DXE30_RS10365	2035813..2037777	-	1965	WP_000870811.1	bacteriocin-associated integral membrane family protein	-
DXE30_RS10370	2037821..2038105	-	285	WP_000790905.1	lactococcin 972 family bacteriocin	-
-	2038650..2038687	+	38	-	-	Antitoxin
DXE30_RS10375	2038740..2038847	-	108	WP_000623369.1	putative holin-like toxin	Toxin
DXE30_RS10380	2039117..2039719	-	603	WP_001033867.1	CPBP family intramembrane metalloprotease	-
DXE30_RS10385	2039734..2039910	-	177	WP_000214898.1	YkvS family protein	-
DXE30_RS10390	2040109..2041095	+	987	WP_000668814.1	lipoate--protein ligase	-
DXE30_RS10395	2041176..2041394	-	219	WP_000876826.1	IDEAL domain-containing protein	-
DXE30_RS10400	2041604..2042173	+	570	WP_000287260.1	competence protein ComK	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3801.69 Da
• Isoelectric Point: 10.8004

>T294174 WP_000623369.1 NZ_LT992466:c2038847-2038740 [Staphylococcus aureus]
VISIANALHLMLSFGMFIVTFIGVVVAIINLNNKK

Nucleotide

• Length: 108 bp

Antitoxin

Nucleotide

• Length: 38 bp

>AT294174 NZ_LT992466:2038650-2038687 [Staphylococcus aureus]
AACATGTCGCCTAATGAGCCCGTTAAAAAGACGGTGAC

Structures

Antitoxin