Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 881438..881717 Replicon chromosome
Accession NZ_LT992466
Organism Staphylococcus aureus isolate 4_LA_208

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag DXE30_RS04350 Protein ID WP_001802298.1
Coordinates 881438..881542 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 881538..881717 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DXE30_RS04315 877337..877945 + 609 WP_000101714.1 TIR domain-containing protein -
DXE30_RS04320 878235..879017 + 783 WP_000908191.1 ABC transporter ATP-binding protein -
DXE30_RS04325 879085..879942 + 858 WP_000370942.1 Cof-type HAD-IIB family hydrolase -
DXE30_RS04330 880072..880164 - 93 WP_000220902.1 hypothetical protein -
DXE30_RS04335 880600..880758 - 159 WP_001792784.1 hypothetical protein -
DXE30_RS04350 881438..881542 + 105 WP_001802298.1 hypothetical protein Toxin
- 881538..881717 - 180 - - Antitoxin
DXE30_RS04355 882040..883131 - 1092 WP_000495673.1 hypothetical protein -
DXE30_RS04360 883397..884377 - 981 WP_000019735.1 CDF family zinc efflux transporter CzrB -
DXE30_RS04365 884379..884699 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
DXE30_RS04370 884851..885516 + 666 WP_001024099.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T294166 WP_001802298.1 NZ_LT992466:881438-881542 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 180 bp

>AT294166 NZ_LT992466:c881717-881538 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTC
AAAGCGAATAGAAGGTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References