Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2048244..2048428 Replicon chromosome
Accession NZ_LT992465
Organism Staphylococcus aureus isolate 6_LA_232

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag DXE62_RS10220 Protein ID WP_000482647.1
Coordinates 2048244..2048351 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2048368..2048428 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DXE62_RS10195 2043601..2044074 + 474 WP_000456489.1 GyrI-like domain-containing protein -
DXE62_RS10200 2044197..2045408 - 1212 WP_001191974.1 multidrug effflux MFS transporter -
DXE62_RS10205 2045596..2046255 - 660 WP_000831300.1 hypothetical protein -
DXE62_RS10210 2046315..2047457 - 1143 WP_001176859.1 glycerate kinase -
DXE62_RS10215 2047724..2048110 + 387 WP_000779355.1 flippase GtxA -
DXE62_RS10220 2048244..2048351 + 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
- 2048368..2048428 - 61 - - Antitoxin
DXE62_RS10230 2049055..2050818 + 1764 WP_001064818.1 ABC transporter ATP-binding protein/permease -
DXE62_RS10235 2050843..2052576 + 1734 WP_000486511.1 ABC transporter ATP-binding protein/permease -
DXE62_RS10245 2052807..2052974 + 168 WP_001798790.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T294154 WP_000482647.1 NZ_LT992465:2048244-2048351 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT294154 NZ_LT992465:c2048428-2048368 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References