Detailed information of TA system TA294150

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 723116..723313
• Replicon: chromosome
• Accession: NZ_LT992465
• Organism: Staphylococcus aureus isolate 6_LA_232

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: DXE62_RS03690
• Protein ID: WP_000623369.1
• Coordinates: 723206..723313 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF3
Locus tag	-
Coordinates	723116..723153 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DXE62_RS03655	718217..718573	+	357	WP_000766009.1	DoxX family protein	-
DXE62_RS03660	718662..718850	-	189	WP_157958947.1	poly(glycerol-phosphate) alpha-glucosyltransferase	-
DXE62_RS03665	718940..719230	+	291	WP_001796515.1	hypothetical protein	-
DXE62_RS03670	719318..719959	-	642	WP_000571192.1	ABC transporter ATP-binding protein	-
DXE62_RS03675	719956..720276	-	321	WP_000668623.1	YxeA family protein	-
DXE62_RS03680	720279..722243	-	1965	WP_000870811.1	bacteriocin-associated integral membrane family protein	-
DXE62_RS03685	722287..722571	-	285	WP_000790905.1	lactococcin 972 family bacteriocin	-
-	723116..723153	+	38	-	-	Antitoxin
DXE62_RS03690	723206..723313	-	108	WP_000623369.1	putative holin-like toxin	Toxin
DXE62_RS03695	723583..724185	-	603	WP_001033867.1	CPBP family intramembrane metalloprotease	-
DXE62_RS03700	724200..724376	-	177	WP_000214898.1	YkvS family protein	-
DXE62_RS03705	724575..725561	+	987	WP_000668814.1	lipoate--protein ligase	-
DXE62_RS03710	725642..725860	-	219	WP_000876826.1	IDEAL domain-containing protein	-
DXE62_RS03715	726070..726639	+	570	WP_000287265.1	competence protein ComK	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3801.69 Da
• Isoelectric Point: 10.8004

>T294150 WP_000623369.1 NZ_LT992465:c723313-723206 [Staphylococcus aureus]
VISIANALHLMLSFGMFIVTFIGVVVAIINLNNKK

Nucleotide

• Length: 108 bp

Antitoxin

Nucleotide

• Length: 38 bp

>AT294150 NZ_LT992465:723116-723153 [Staphylococcus aureus]
AACATGTCGCCTAATGAGCCCGTTAAAAAGACGGTGAC

Structures

Antitoxin