Detailed information of TA system TA294140

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 1577472..1577669
• Replicon: chromosome
• Accession: NZ_LT992464
• Organism: Staphylococcus aureus isolate 3_LA_115

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: DXE56_RS08305
• Protein ID: WP_000623369.1
• Coordinates: 1577562..1577669 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF3
Locus tag	-
Coordinates	1577472..1577509 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DXE56_RS08270	1572573..1572929	+	357	WP_000766009.1	DoxX family protein	-
DXE56_RS08275	1573018..1573206	-	189	WP_157958947.1	poly(glycerol-phosphate) alpha-glucosyltransferase	-
DXE56_RS08280	1573296..1573586	+	291	WP_001796515.1	hypothetical protein	-
DXE56_RS08285	1573674..1574315	-	642	WP_000571192.1	ABC transporter ATP-binding protein	-
DXE56_RS08290	1574312..1574632	-	321	WP_000668623.1	YxeA family protein	-
DXE56_RS08295	1574635..1576599	-	1965	WP_000870811.1	bacteriocin-associated integral membrane family protein	-
DXE56_RS08300	1576643..1576927	-	285	WP_000790905.1	lactococcin 972 family bacteriocin	-
-	1577472..1577509	+	38	-	-	Antitoxin
DXE56_RS08305	1577562..1577669	-	108	WP_000623369.1	putative holin-like toxin	Toxin
DXE56_RS08310	1577939..1578541	-	603	WP_001033867.1	CPBP family intramembrane metalloprotease	-
DXE56_RS08315	1578556..1578732	-	177	WP_000214898.1	YkvS family protein	-
DXE56_RS08320	1578931..1579917	+	987	WP_000668814.1	lipoate--protein ligase	-
DXE56_RS08325	1579998..1580216	-	219	WP_000876826.1	IDEAL domain-containing protein	-
DXE56_RS08330	1580426..1580995	+	570	WP_000287265.1	competence protein ComK	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3801.69 Da
• Isoelectric Point: 10.8004

>T294140 WP_000623369.1 NZ_LT992464:c1577669-1577562 [Staphylococcus aureus]
VISIANALHLMLSFGMFIVTFIGVVVAIINLNNKK

Nucleotide

• Length: 108 bp

Antitoxin

Nucleotide

• Length: 38 bp

>AT294140 NZ_LT992464:1577472-1577509 [Staphylococcus aureus]
AACATGTCGCCTAATGAGCCCGTTAAAAAGACGGTGAC

Structures

Antitoxin