Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 114211..114395 Replicon chromosome
Accession NZ_LT992464
Organism Staphylococcus aureus isolate 3_LA_115

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag DXE56_RS00580 Protein ID WP_000482647.1
Coordinates 114211..114318 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 114335..114395 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DXE56_RS00555 109568..110041 + 474 WP_000456489.1 GyrI-like domain-containing protein -
DXE56_RS00560 110164..111375 - 1212 WP_001191974.1 multidrug effflux MFS transporter -
DXE56_RS00565 111563..112222 - 660 WP_000831300.1 hypothetical protein -
DXE56_RS00570 112282..113424 - 1143 WP_001176859.1 glycerate kinase -
DXE56_RS00575 113691..114077 + 387 WP_000779355.1 flippase GtxA -
DXE56_RS00580 114211..114318 + 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
- 114335..114395 - 61 - - Antitoxin
DXE56_RS00590 115022..116785 + 1764 WP_001064818.1 ABC transporter ATP-binding protein/permease -
DXE56_RS00595 116810..118543 + 1734 WP_000486511.1 ABC transporter ATP-binding protein/permease -
DXE56_RS00605 118774..118941 + 168 WP_001798790.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T294130 WP_000482647.1 NZ_LT992464:114211-114318 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp


Antitoxin


Download         Length: 61 bp

>AT294130 NZ_LT992464:c114395-114335 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7


Antitoxin

Download structure file

References