Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2674084..2674268 Replicon chromosome
Accession NZ_LT992463
Organism Staphylococcus aureus isolate 2_LA_86

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag DXE29_RS13690 Protein ID WP_000482647.1
Coordinates 2674161..2674268 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2674084..2674144 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DXE29_RS13665 2669538..2669705 - 168 WP_001798790.1 hypothetical protein -
DXE29_RS13675 2669936..2671669 - 1734 WP_000486511.1 ABC transporter ATP-binding protein/permease -
DXE29_RS13680 2671694..2673457 - 1764 WP_001064818.1 ABC transporter ATP-binding protein/permease -
- 2674084..2674144 + 61 - - Antitoxin
DXE29_RS13690 2674161..2674268 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
DXE29_RS13695 2674402..2674788 - 387 WP_000779355.1 flippase GtxA -
DXE29_RS13700 2675055..2676197 + 1143 WP_001176859.1 glycerate kinase -
DXE29_RS13705 2676257..2676916 + 660 WP_000831300.1 hypothetical protein -
DXE29_RS13710 2677104..2678315 + 1212 WP_001191974.1 multidrug effflux MFS transporter -
DXE29_RS13715 2678438..2678911 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T294126 WP_000482647.1 NZ_LT992463:c2674268-2674161 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT294126 NZ_LT992463:2674084-2674144 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References