Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | sprG-sprF/- |
Location | 2378324..2378541 | Replicon | chromosome |
Accession | NZ_LT992463 | ||
Organism | Staphylococcus aureus isolate 2_LA_86 |
Toxin (Protein)
Gene name | SprG3 | Uniprot ID | Q2FWA7 |
Locus tag | DXE29_RS12075 | Protein ID | WP_001802298.1 |
Coordinates | 2378437..2378541 (-) | Length | 35 a.a. |
Antitoxin (RNA)
Gene name | SprF1 | ||
Locus tag | - | ||
Coordinates | 2378324..2378379 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
DXE29_RS12055 | 2374463..2375128 | - | 666 | WP_001024099.1 | SDR family oxidoreductase | - |
DXE29_RS12060 | 2375280..2375600 | + | 321 | WP_000003759.1 | Zn(II)-responsive metalloregulatory transcriptional repressor CzrA | - |
DXE29_RS12065 | 2375602..2376582 | + | 981 | WP_000019735.1 | CDF family zinc efflux transporter CzrB | - |
DXE29_RS12070 | 2376848..2377939 | + | 1092 | WP_000495673.1 | hypothetical protein | - |
- | 2378324..2378379 | + | 56 | - | - | Antitoxin |
DXE29_RS12075 | 2378437..2378541 | - | 105 | WP_001802298.1 | hypothetical protein | Toxin |
DXE29_RS12090 | 2379221..2379379 | + | 159 | WP_001792784.1 | hypothetical protein | - |
DXE29_RS12100 | 2380037..2380894 | - | 858 | WP_000370942.1 | Cof-type HAD-IIB family hydrolase | - |
DXE29_RS12105 | 2380962..2381744 | - | 783 | WP_000908191.1 | ABC transporter ATP-binding protein | - |
DXE29_RS12110 | 2382034..2382642 | - | 609 | WP_000101714.1 | TIR domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 35 a.a. Molecular weight: 3906.77 Da Isoelectric Point: 5.5724
>T294124 WP_001802298.1 NZ_LT992463:c2378541-2378437 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
Download Length: 105 bp
Antitoxin
Download Length: 56 bp
>AT294124 NZ_LT992463:2378324-2378379 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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