Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 1960533..1960812 Replicon chromosome
Accession NZ_LT992462
Organism Staphylococcus aureus isolate 5_3949

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag DXE65_RS10500 Protein ID WP_001802298.1
Coordinates 1960708..1960812 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 1960533..1960712 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DXE65_RS10480 1956734..1957399 - 666 WP_001024099.1 SDR family oxidoreductase -
DXE65_RS10485 1957551..1957871 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
DXE65_RS10490 1957873..1958853 + 981 WP_000019735.1 CDF family zinc efflux transporter CzrB -
DXE65_RS10495 1959119..1960210 + 1092 WP_000495673.1 hypothetical protein -
- 1960533..1960712 + 180 - - Antitoxin
DXE65_RS10500 1960708..1960812 - 105 WP_001802298.1 hypothetical protein Toxin
DXE65_RS15545 1961329..1961499 + 171 WP_001807897.1 hypothetical protein -
DXE65_RS10515 1961492..1961650 + 159 WP_001792784.1 hypothetical protein -
DXE65_RS10520 1962086..1962178 + 93 WP_000220902.1 hypothetical protein -
DXE65_RS10525 1962308..1963165 - 858 WP_000370942.1 Cof-type HAD-IIB family hydrolase -
DXE65_RS10530 1963233..1964015 - 783 WP_000908191.1 ABC transporter ATP-binding protein -
DXE65_RS10535 1964305..1964913 - 609 WP_000101714.1 TIR domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T294111 WP_001802298.1 NZ_LT992462:c1960812-1960708 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 180 bp

>AT294111 NZ_LT992462:1960533-1960712 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTC
AAAGCGAATAGAAGGTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References