Detailed information of TA system TA294097

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 537285..537534
• Replicon: chromosome
• Accession: NZ_LT992462
• Organism: Staphylococcus aureus isolate 5_3949

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: DXE65_RS02590
• Protein ID: WP_000623369.1
• Coordinates: 537427..537534 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF2
Locus tag	-
Coordinates	537285..537432 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DXE65_RS02555	532438..532794	+	357	WP_000766009.1	DoxX family protein	-
DXE65_RS02560	532883..533071	-	189	WP_157958947.1	poly(glycerol-phosphate) alpha-glucosyltransferase	-
DXE65_RS02565	533161..533451	+	291	WP_001796515.1	hypothetical protein	-
DXE65_RS02570	533539..534180	-	642	WP_000571192.1	ABC transporter ATP-binding protein	-
DXE65_RS02575	534177..534497	-	321	WP_000668623.1	YxeA family protein	-
DXE65_RS02580	534500..536464	-	1965	WP_000870811.1	bacteriocin-associated integral membrane family protein	-
DXE65_RS02585	536508..536792	-	285	WP_000790905.1	lactococcin 972 family bacteriocin	-
-	537285..537432	+	148	-	-	Antitoxin
DXE65_RS02590	537427..537534	-	108	WP_000623369.1	putative holin-like toxin	Toxin
DXE65_RS02595	537804..538406	-	603	WP_001033867.1	CPBP family intramembrane metalloprotease	-
DXE65_RS02600	538421..538597	-	177	WP_000214898.1	YkvS family protein	-
DXE65_RS02605	538796..539782	+	987	WP_000668814.1	lipoate--protein ligase	-
DXE65_RS02610	539863..540081	-	219	WP_000876826.1	IDEAL domain-containing protein	-
DXE65_RS02615	540291..540860	+	570	WP_000287265.1	competence protein ComK	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3801.69 Da
• Isoelectric Point: 10.8004

>T294097 WP_000623369.1 NZ_LT992462:c537534-537427 [Staphylococcus aureus]
VISIANALHLMLSFGMFIVTFIGVVVAIINLNNKK

Nucleotide

• Length: 108 bp

Antitoxin

Nucleotide

• Length: 148 bp

>AT294097 NZ_LT992462:537285-537432 [Staphylococcus aureus]
CAATTAAATAAAAGATATGTTACTATAAAAATGTAAAAAGACGACATGCAGTAACATGTCGCCTAATGAGCCCGTTAAAA
AGACGGTGACTAAATGAGATTTGCTTTAACCATCATTCGTTGTCAAAGTTTTGAAATGATGGTTATTT

Structures

Antitoxin