Detailed information of TA system TA294080

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2738202..2738399
• Replicon: chromosome
• Accession: NZ_LT992460
• Organism: Staphylococcus aureus isolate 9_LA_281

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: DXE39_RS14220
• Protein ID: WP_000623369.1
• Coordinates: 2738292..2738399 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF3
Locus tag	-
Coordinates	2738202..2738239 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DXE39_RS14185	2733303..2733659	+	357	WP_000766009.1	DoxX family protein	-
DXE39_RS14190	2733748..2733936	-	189	WP_157958947.1	poly(glycerol-phosphate) alpha-glucosyltransferase	-
DXE39_RS14195	2734026..2734316	+	291	WP_001796515.1	hypothetical protein	-
DXE39_RS14200	2734404..2735045	-	642	WP_000571192.1	ABC transporter ATP-binding protein	-
DXE39_RS14205	2735042..2735362	-	321	WP_000668623.1	YxeA family protein	-
DXE39_RS14210	2735365..2737329	-	1965	WP_000870811.1	bacteriocin-associated integral membrane family protein	-
DXE39_RS14215	2737373..2737657	-	285	WP_000790905.1	lactococcin 972 family bacteriocin	-
-	2738202..2738239	+	38	-	-	Antitoxin
DXE39_RS14220	2738292..2738399	-	108	WP_000623369.1	putative holin-like toxin	Toxin
DXE39_RS14225	2738669..2739271	-	603	WP_001033867.1	CPBP family intramembrane metalloprotease	-
DXE39_RS14230	2739286..2739463	-	178	Protein_2638	YkvS family protein	-
DXE39_RS14235	2739662..2740648	+	987	WP_000668814.1	lipoate--protein ligase	-
DXE39_RS14240	2740729..2740947	-	219	WP_000876826.1	IDEAL domain-containing protein	-
DXE39_RS14245	2741157..2741726	+	570	WP_000287265.1	competence protein ComK	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3801.69 Da
• Isoelectric Point: 10.8004

>T294080 WP_000623369.1 NZ_LT992460:c2738399-2738292 [Staphylococcus aureus]
VISIANALHLMLSFGMFIVTFIGVVVAIINLNNKK

Nucleotide

• Length: 108 bp

>T294080 NZ_LT992460:c2738399-2738292 [Staphylococcus aureus]
GTGATATCTATTGCAAATGCATTACATTTAATGTTAAGTTTCGGTATGTTTATCGTCACTTTCATTGGTGTAGTAGTCGC
AATAATTAATTTAAACAATAAAAAATAA

Antitoxin

Nucleotide

• Length: 38 bp

>AT294080 NZ_LT992460:2738202-2738239 [Staphylococcus aureus]
AACATGTCGCCTAATGAGCCCGTTAAAAAGACGGTGAC

Structures

Antitoxin