294074

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 1569809..1570072 Replicon chromosome
Accession NZ_LT992460
Organism Staphylococcus aureus isolate 9_LA_281

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag DXE39_RS08115 Protein ID WP_001802298.1
Coordinates 1569809..1569913 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 1569908..1570072 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DXE39_RS08080 1565708..1566316 + 609 WP_000101714.1 TIR domain-containing protein -
DXE39_RS08085 1566606..1567388 + 783 WP_000908191.1 ABC transporter ATP-binding protein -
DXE39_RS08090 1567456..1568313 + 858 WP_000370942.1 Cof-type HAD-IIB family hydrolase -
DXE39_RS08095 1568443..1568535 - 93 WP_000220902.1 hypothetical protein -
DXE39_RS08100 1568971..1569129 - 159 WP_001792784.1 hypothetical protein -
DXE39_RS08115 1569809..1569913 + 105 WP_001802298.1 hypothetical protein Toxin
- 1569908..1570072 - 165 - - Antitoxin
DXE39_RS08120 1570411..1571502 - 1092 WP_000495673.1 hypothetical protein -
DXE39_RS08125 1571768..1572748 - 981 WP_000019735.1 CDF family zinc efflux transporter CzrB -
DXE39_RS08130 1572750..1573070 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
DXE39_RS08135 1573222..1573887 + 666 WP_001024099.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T294074 WP_001802298.1 NZ_LT992460:1569809-1569913 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 165 bp

>AT294074 NZ_LT992460:c1570072-1569908 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References