Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 1927112..1927375 Replicon chromosome
Accession NZ_LT992456
Organism Staphylococcus aureus isolate 1_1439

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag DXE58_RS09740 Protein ID WP_001802298.1
Coordinates 1927112..1927216 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 1927211..1927375 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DXE58_RS09705 1923011..1923619 + 609 WP_000101714.1 TIR domain-containing protein -
DXE58_RS09710 1923909..1924691 + 783 WP_000908191.1 ABC transporter ATP-binding protein -
DXE58_RS09715 1924759..1925616 + 858 WP_000370942.1 Cof-type HAD-IIB family hydrolase -
DXE58_RS09720 1925746..1925838 - 93 WP_000220902.1 hypothetical protein -
DXE58_RS09725 1926274..1926432 - 159 WP_001792784.1 hypothetical protein -
DXE58_RS09740 1927112..1927216 + 105 WP_001802298.1 hypothetical protein Toxin
- 1927211..1927375 - 165 - - Antitoxin
DXE58_RS09745 1927648..1928739 - 1092 WP_000495673.1 hypothetical protein -
DXE58_RS09750 1929005..1929985 - 981 WP_000019735.1 CDF family zinc efflux transporter CzrB -
DXE58_RS09755 1929987..1930307 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
DXE58_RS09760 1930459..1931124 + 666 WP_001024099.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T294037 WP_001802298.1 NZ_LT992456:1927112-1927216 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 165 bp

>AT294037 NZ_LT992456:c1927375-1927211 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References