Detailed information of TA system TA294032

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 291886..292083
• Replicon: chromosome
• Accession: NZ_LT992456
• Organism: Staphylococcus aureus isolate 1_1439

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: DXE58_RS01485
• Protein ID: WP_000623369.1
• Coordinates: 291976..292083 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF3
Locus tag	-
Coordinates	291886..291923 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DXE58_RS01450	286987..287343	+	357	WP_000766009.1	DoxX family protein	-
DXE58_RS01455	287432..287620	-	189	WP_157958947.1	poly(glycerol-phosphate) alpha-glucosyltransferase	-
DXE58_RS01460	287710..288000	+	291	WP_001796515.1	hypothetical protein	-
DXE58_RS01465	288088..288729	-	642	WP_000571192.1	ABC transporter ATP-binding protein	-
DXE58_RS01470	288726..289046	-	321	WP_000668623.1	YxeA family protein	-
DXE58_RS01475	289049..291013	-	1965	WP_000870811.1	bacteriocin-associated integral membrane family protein	-
DXE58_RS01480	291057..291341	-	285	WP_000790905.1	lactococcin 972 family bacteriocin	-
-	291886..291923	+	38	-	-	Antitoxin
DXE58_RS01485	291976..292083	-	108	WP_000623369.1	putative holin-like toxin	Toxin
DXE58_RS01490	292353..292955	-	603	WP_001033867.1	CPBP family intramembrane metalloprotease	-
DXE58_RS01495	292970..293146	-	177	WP_000214898.1	YkvS family protein	-
DXE58_RS01500	293345..294331	+	987	WP_000668814.1	lipoate--protein ligase	-
DXE58_RS01505	294412..294630	-	219	WP_000876826.1	IDEAL domain-containing protein	-
DXE58_RS01510	294840..295409	+	570	WP_000287260.1	competence protein ComK	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3801.69 Da
• Isoelectric Point: 10.8004

>T294032 WP_000623369.1 NZ_LT992456:c292083-291976 [Staphylococcus aureus]
VISIANALHLMLSFGMFIVTFIGVVVAIINLNNKK

Nucleotide

• Length: 108 bp

Antitoxin

Nucleotide

• Length: 38 bp

>AT294032 NZ_LT992456:291886-291923 [Staphylococcus aureus]
AACATGTCGCCTAATGAGCCCGTTAAAAAGACGGTGAC

Structures

Antitoxin