Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 1446561..1446745 Replicon chromosome
Accession NZ_LT992435
Organism Staphylococcus aureus isolate 1549-SCV

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag DYY96_RS07620 Protein ID WP_000482647.1
Coordinates 1446638..1446745 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 1446561..1446621 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DYY96_RS07600 1442148..1442315 - 168 WP_031785511.1 hypothetical protein -
DYY96_RS07610 1442546..1444278 - 1733 Protein_1407 ABC transporter ATP-binding protein -
DYY96_RS07615 1444327..1446066 - 1740 WP_115657082.1 ABC transporter ATP-binding protein/permease -
DYY96_RS14055 1446444..1446611 - 168 WP_000301894.1 hypothetical protein -
- 1446561..1446621 + 61 - - Antitoxin
DYY96_RS07620 1446638..1446745 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
DYY96_RS07625 1446879..1447265 - 387 WP_000779354.1 flippase GtxA -
DYY96_RS07630 1447533..1448675 + 1143 WP_001176860.1 glycerate kinase -
DYY96_RS07635 1448735..1449394 + 660 WP_000831298.1 membrane protein -
DYY96_RS07640 1449574..1450785 + 1212 WP_001191975.1 multidrug effflux MFS transporter -
DYY96_RS07645 1450908..1451381 - 474 WP_000456491.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T294021 WP_000482647.1 NZ_LT992435:c1446745-1446638 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT294021 NZ_LT992435:1446561-1446621 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References