Detailed information of TA system
Overview
TA module
| Type | I | Classification (family/domain) | sprA1-sprA1AS/- |
| Location | 2437496..2437653 | Replicon | chromosome |
| Accession | NZ_LT963436 | ||
| Organism | Staphylococcus saprophyticus isolate Staphylococcus saprophyticus 883 | ||
Toxin (Protein)
| Gene name | sprA1 | Uniprot ID | - |
| Locus tag | DG022_RS12005 | Protein ID | WP_002441941.1 |
| Coordinates | 2437558..2437653 (-) | Length | 32 a.a. |
Antitoxin (RNA)
| Gene name | sprA1AS | ||
| Locus tag | - | ||
| Coordinates | 2437496..2437529 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| DG022_RS11980 | 2433283..2434116 | + | 834 | WP_069795006.1 | aldo/keto reductase | - |
| DG022_RS11985 | 2434583..2434882 | - | 300 | WP_011304021.1 | hypothetical protein | - |
| DG022_RS11990 | 2435259..2435492 | + | 234 | WP_011304022.1 | ferrous iron transport protein A | - |
| DG022_RS11995 | 2435553..2435618 | - | 66 | WP_108866175.1 | type I toxin-antitoxin system Fst family toxin | - |
| DG022_RS12000 | 2435806..2437200 | - | 1395 | WP_078073159.1 | RES family NAD+ phosphorylase | - |
| - | 2437496..2437529 | + | 34 | - | - | Antitoxin |
| DG022_RS12005 | 2437558..2437653 | - | 96 | WP_002441941.1 | type I toxin-antitoxin system Fst family toxin | Toxin |
| DG022_RS12010 | 2437956..2438714 | - | 759 | WP_069795223.1 | MerR family transcriptional regulator | - |
| DG022_RS12015 | 2438824..2439387 | - | 564 | WP_047505113.1 | helix-turn-helix domain-containing protein | - |
| DG022_RS12020 | 2439581..2441038 | - | 1458 | WP_011304026.1 | carbon starvation protein A | - |
| DG022_RS12025 | 2441246..2442085 | - | 840 | WP_002481957.1 | ParB/RepB/Spo0J family partition protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 32 a.a. Molecular weight: 3560.34 Da Isoelectric Point: 9.9256
>T293941 WP_002441941.1 NZ_LT963436:c2437653-2437558 [Staphylococcus saprophyticus]
MLMIFVHIIAPVISGCAVAYFTYWLSSKRNK
MLMIFVHIIAPVISGCAVAYFTYWLSSKRNK
Download Length: 96 bp
Antitoxin
Download Length: 34 bp
>AT293941 NZ_LT963436:2437496-2437529 [Staphylococcus saprophyticus]
CACCAATCCCCTCACTATTTGCGGTAGTGAGGGG
CACCAATCCCCTCACTATTTGCGGTAGTGAGGGG
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|