293854

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-MqsA
Location 42416..43049 Replicon plasmid P
Accession NZ_LT960613
Organism Vibrio tapetis subsp. tapetis isolate Vibrio tapetis CECT4600

Toxin (Protein)


Gene name higB Uniprot ID B2LS89
Locus tag VTAP4600_RS25545 Protein ID WP_012397026.1
Coordinates 42416..42748 (+) Length 111 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag VTAP4600_RS25550 Protein ID WP_012397027.1
Coordinates 42735..43049 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
VTAP4600_RS25525 37854..38189 - 336 WP_012397022.1 hypothetical protein -
VTAP4600_RS25530 38274..38660 - 387 WP_012397023.1 hypothetical protein -
VTAP4600_RS25535 38684..39028 - 345 WP_012397024.1 hypothetical protein -
VTAP4600_RS25540 39712..41535 - 1824 WP_102525550.1 ParB/RepB/Spo0J family partition protein -
VTAP4600_RS25545 42416..42748 + 333 WP_012397026.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
VTAP4600_RS25550 42735..43049 + 315 WP_012397027.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
VTAP4600_RS25555 43465..43956 + 492 WP_012397028.1 RDD family protein -
VTAP4600_RS25560 44552..46084 + 1533 WP_102521770.1 IS21 family transposase -
VTAP4600_RS25565 46094..46834 + 741 WP_012397030.1 IS21-like element helper ATPase IstB -
VTAP4600_RS25570 46979..47446 + 468 WP_012397031.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..82266 82266


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(11-104)

Antitoxin

Cro/C1-type helix-turn-helix domain

(43-92)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 12983.80 Da        Isoelectric Point: 9.9244

>T293854 WP_012397026.1 NZ_LT960613:42416-42748 [Vibrio tapetis subsp. tapetis]
MRSIFVESTIFEKYRYEYLSDDEFRLFQAELMSNPNQGDVIQGTGGLRKIRVASKGKGKRGGSRVIYYFLDEKRRFYLLT
IYGKNEMSDLTADQKKQLKAFMEAWRNEQS

Download         Length: 333 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11874.41 Da        Isoelectric Point: 7.0749

>AT293854 WP_012397027.1 NZ_LT960613:42735-43049 [Vibrio tapetis subsp. tapetis]
MSNRDLFAELSSALVEAKEHSEGKLTLKNHQFNDISELNISPDEIMRIREHFNMSRGVFARLLHTSSRTLENWEQGRSAP
NGQAVTLLKLVQRHPETLSHIAQL

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2N8ZNQ3

Antitoxin

Source ID Structure

References