Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-MqsA
Location 3646263..3646896 Replicon chromosome
Accession NZ_LT960611
Organism Vibrio tapetis subsp. tapetis isolate Vibrio tapetis CECT4600

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag VTAP4600_RS16400 Protein ID WP_102523754.1
Coordinates 3646263..3646595 (+) Length 111 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag VTAP4600_RS16405 Protein ID WP_012397027.1
Coordinates 3646582..3646896 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
VTAP4600_RS16395 3644519..3645382 - 864 WP_102523753.1 ParB/RepB/Spo0J family partition protein -
VTAP4600_RS16400 3646263..3646595 + 333 WP_102523754.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
VTAP4600_RS16405 3646582..3646896 + 315 WP_012397027.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
VTAP4600_RS16410 3647312..3647803 + 492 WP_012397028.1 RDD family protein -
VTAP4600_RS16415 3648399..3649931 + 1533 WP_102521770.1 IS21 family transposase -
VTAP4600_RS16420 3649941..3650681 + 741 WP_012397030.1 IS21-like element helper ATPase IstB -
VTAP4600_RS16425 3650826..3651293 + 468 WP_012397031.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(11-104)

Antitoxin

Cro/C1-type helix-turn-helix domain

(43-92)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 12997.87 Da        Isoelectric Point: 10.0511

>T293847 WP_102523754.1 NZ_LT960611:3646263-3646595 [Vibrio tapetis subsp. tapetis]
MRSIFVESTIFEKYRYEYLSDDEFRLFQAELMSNPKQGDVIQGTGGLRKIRVASKGKGKRGGSRVIYYFLDEKRRFYLLT
IYGKNEMSDLTADQKKQLKAFMEAWRNEQS

Download         Length: 333 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11874.41 Da        Isoelectric Point: 7.0749

>AT293847 WP_012397027.1 NZ_LT960611:3646582-3646896 [Vibrio tapetis subsp. tapetis]
MSNRDLFAELSSALVEAKEHSEGKLTLKNHQFNDISELNISPDEIMRIREHFNMSRGVFARLLHTSSRTLENWEQGRSAP
NGQAVTLLKLVQRHPETLSHIAQL

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References