Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-VapI
Location 1538765..1539354 Replicon chromosome
Accession NZ_LT906473
Organism Corynebacterium cystitidis strain NCTC11863

Toxin (Protein)


Gene name graT Uniprot ID -
Locus tag CKV99_RS07220 Protein ID WP_092256838.1
Coordinates 1539073..1539354 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag CKV99_RS07215 Protein ID WP_092256841.1
Coordinates 1538765..1539064 (-) Length 100 a.a.

Genomic Context

CKV99_RS07190CKV99_RS07200CKV99_RS07205CKV99_RS07210CKV99_RS07230CKV99_RS07235CKV99_RS07240CKV99_RS07195CKV99_RS07215CKV99_RS07220CKV99_RS07225
Location: 1533945..1534742 (798 bp)
Type: Others
Protein ID: WP_092257332.1
Location: 1535288..1536694 (1407 bp)
Type: Others
Protein ID: WP_092256849.1
Location: 1536743..1538305 (1563 bp)
Type: Others
Protein ID: WP_157728391.1
Location: 1538302..1538571 (270 bp)
Type: Others
Protein ID: WP_092256844.1
Location: 1540554..1542023 (1470 bp)
Type: Others
Protein ID: WP_092257329.1
Location: 1542053..1543147 (1095 bp)
Type: Others
Protein ID: WP_092257327.1
Location: 1543283..1543888 (606 bp)
Type: Others
Protein ID: WP_092256830.1
Location: 1534739..1535245 (507 bp)
Type: Others
Protein ID: WP_092256852.1
Location: 1538765..1539064 (300 bp)
Type: Antitoxin
Protein ID: WP_092256841.1
Location: 1539073..1539354 (282 bp)
Type: Toxin
Protein ID: WP_092256838.1
Location: 1539395..1540480 (1086 bp)
Type: Others
Protein ID: WP_092256835.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
CKV99_RS071901533945..1534742+798WP_092257332.1fused MFS/spermidine synthase-
CKV99_RS071951534739..1535245-507WP_092256852.12'-5' RNA ligase family protein-
CKV99_RS072001535288..1536694+1407WP_092256849.1DNA photolyase family protein-
CKV99_RS072051536743..1538305+1563WP_157728391.1DNA/RNA non-specific endonuclease-
CKV99_RS072101538302..1538571+270WP_092256844.1hypothetical protein-
CKV99_RS072151538765..1539064-300WP_092256841.1HigA family addiction module antidote proteinAntitoxin
CKV99_RS072201539073..1539354-282WP_092256838.1type II toxin-antitoxin system RelE/ParE family toxinToxin
CKV99_RS072251539395..1540480-1086WP_092256835.1redox-regulated ATPase YchF-
CKV99_RS072301540554..1542023+1470WP_092257329.1AI-2E family transporter-
CKV99_RS072351542053..1543147+1095WP_092257327.1DNA recombination protein RmuC-
CKV99_RS072401543283..1543888+606WP_092256830.1MFS transporter-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(4-93)

Antitoxin

Cro/C1-type helix-turn-helix domain

(18-68)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10906.57 Da        Isoelectric Point: 10.3438

>T293739 WP_092256838.1 NZ_LT906473:c1539354-1539073 [Corynebacterium cystitidis]
VIVSFADKDTERLFRRQRPKRIDTRLQRRALSKLLVLNAAVKLEELKVPPGNQLELLSGDRVGQHSIRINSQWRICFVWT
DEGPRDVEIVDYH

Download         Length: 282 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 11137.88 Da        Isoelectric Point: 6.0691

>AT293739 WP_092256841.1 NZ_LT906473:c1539064-1538765 [Corynebacterium cystitidis]
MDTKTLPPIHPGEILMEEFLDPLQITQHKLAVAIGVPPRRINEIVHGKRRITADTALRLGRYLGMTAQFWINLQSHYDLE
VEGEAIADQLDAISPLRTA

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References