Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-sprA1AS/-
Location 2505476..2505634 Replicon chromosome
Accession NZ_LT906460
Organism Staphylococcus simiae strain NCTC13838

Toxin (Protein)


Gene name SprA2 Uniprot ID -
Locus tag CKV88_RS12515 Protein ID WP_002463737.1
Coordinates 2505476..2505571 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2505596..2505634 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CKV88_RS11770 2501048..2501527 - 480 WP_002463725.1 hypothetical protein -
CKV88_RS11775 2501743..2502189 + 447 WP_002463727.1 glyoxalase/bleomycin resistance/extradiol dioxygenase family protein -
CKV88_RS11780 2502347..2502730 - 384 WP_040801911.1 aspartate 1-decarboxylase -
CKV88_RS11785 2502730..2503584 - 855 WP_002463732.1 pantoate--beta-alanine ligase -
CKV88_RS11790 2503577..2504395 - 819 WP_002463734.1 3-methyl-2-oxobutanoate hydroxymethyltransferase -
CKV88_RS11795 2504468..2505334 + 867 WP_002463736.1 oxidoreductase -
CKV88_RS12515 2505476..2505571 + 96 WP_002463737.1 type I toxin-antitoxin system Fst family toxin Toxin
- 2505596..2505634 - 39 - - Antitoxin
CKV88_RS11800 2505770..2506474 - 705 WP_002463739.1 acetolactate decarboxylase -
CKV88_RS11805 2506750..2507709 - 960 WP_002463741.1 L-lactate dehydrogenase -
CKV88_RS11810 2508255..2509703 + 1449 WP_002463743.1 amino acid permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3531.15 Da        Isoelectric Point: 9.6659

>T293722 WP_002463737.1 NZ_LT906460:2505476-2505571 [Staphylococcus simiae]
MLETLVNTATTVISGCIIALFTHWLRNRNNK

Download         Length: 96 bp

Antitoxin


Download         Length: 39 bp

>AT293722 NZ_LT906460:c2505634-2505596 [Staphylococcus simiae]
TATGCACCTAGTCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References