Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-SprA2AS/-
Location 1372390..1372569 Replicon chromosome
Accession NZ_LT906460
Organism Staphylococcus simiae strain NCTC13838

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag CKV88_RS12485 Protein ID WP_002465043.1
Coordinates 1372474..1372569 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 1372390..1372448 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CKV88_RS06335 1368470..1369417 - 948 WP_002465040.1 phosphate ABC transporter substrate-binding protein PstS family protein -
CKV88_RS06340 1369681..1370586 - 906 WP_002465041.1 RNA-binding virulence regulatory protein CvfB -
CKV88_RS06345 1370732..1372333 + 1602 WP_002465042.1 ATP-binding cassette domain-containing protein -
- 1372390..1372448 + 59 - - Antitoxin
CKV88_RS12485 1372474..1372569 - 96 WP_002465043.1 type I toxin-antitoxin system Fst family toxin Toxin
CKV88_RS06350 1374163..1375365 + 1203 WP_002462932.1 aspartate kinase -
CKV88_RS06355 1375429..1376418 + 990 WP_002462930.1 aspartate-semialdehyde dehydrogenase -
CKV88_RS06360 1376420..1377304 + 885 WP_002462928.1 4-hydroxy-tetrahydrodipicolinate synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3479.21 Da        Isoelectric Point: 9.2007

>T293716 WP_002465043.1 NZ_LT906460:c1372569-1372474 [Staphylococcus simiae]
MSMVIINVLGTIISGCAIAFFTYWLNEKSKK

Download         Length: 96 bp

Antitoxin


Download         Length: 59 bp

>AT293716 NZ_LT906460:1372390-1372448 [Staphylococcus simiae]
ACATTATAACCATTGACATGGCAAACACAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References