293635

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-YefM
Location 3008022..3008569 Replicon chromosome
Accession NZ_LT900217
Organism Gordonibacter urolithinfaciens strain DSM 27213T

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag BN3560_RS12875 Protein ID WP_087190613.1
Coordinates 3008276..3008569 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag BN3560_RS12870 Protein ID WP_087190612.1
Coordinates 3008022..3008273 (+) Length 84 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BN3560_RS12845 3003400..3004068 + 669 WP_015539919.1 TetR/AcrR family transcriptional regulator -
BN3560_RS12850 3004093..3004317 - 225 WP_096228356.1 hypothetical protein -
BN3560_RS12855 3004362..3004904 - 543 WP_096228357.1 hypothetical protein -
BN3560_RS12860 3005016..3005375 - 360 WP_096228358.1 oxidoreductase -
BN3560_RS12865 3005375..3007753 - 2379 WP_161959474.1 molybdopterin-dependent oxidoreductase -
BN3560_RS12870 3008022..3008273 + 252 WP_087190612.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
BN3560_RS12875 3008276..3008569 + 294 WP_087190613.1 Txe/YoeB family addiction module toxin Toxin
BN3560_RS12880 3008606..3010066 - 1461 WP_096228360.1 helix-turn-helix transcriptional regulator -
BN3560_RS12885 3010320..3010592 - 273 WP_087190615.1 hypothetical protein -
BN3560_RS12890 3010703..3012088 - 1386 WP_096228361.1 MFS transporter -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(3-70)

Antitoxin

(1-71)


Sequences


Toxin        


Download         Length: 98 a.a.        Molecular weight: 10950.62 Da        Isoelectric Point: 9.5769

>T293635 WP_087190613.1 NZ_LT900217:3008276-3008569 [Gordonibacter urolithinfaciens]
MYAVKFTKQAAKDAKKLKAAGLDKKAKALVEVLKNDPFQEAPAYETLVGNLSGLYSRRINLQHRLVYQVYAEPFAEGGEE
FDGTVKVVRMWTHYEGL

Download         Length: 294 bp


Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9015.18 Da        Isoelectric Point: 4.0863

>AT293635 WP_087190612.1 NZ_LT900217:3008022-3008273 [Gordonibacter urolithinfaciens]
MTSITATALRQNIYQTIAQVNENCTPIAITNSKGKGAVLIGESDWAAIEETLFLNGIPGMSESLRAGMAEKPEDCLSEDR
LEW

Download         Length: 252 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References