Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 51723..52394 Replicon chromosome
Accession NZ_LT900217
Organism Gordonibacter urolithinfaciens strain DSM 27213T

Toxin (Protein)


Gene name HigB2 Uniprot ID -
Locus tag BN3560_RS00240 Protein ID WP_096226529.1
Coordinates 52029..52394 (-) Length 122 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag BN3560_RS00235 Protein ID WP_096226528.1
Coordinates 51723..52025 (-) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BN3560_RS00215 46839..48236 - 1398 WP_087189762.1 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB -
BN3560_RS00220 48245..48601 - 357 WP_087189761.1 stage V sporulation protein S -
BN3560_RS00225 48774..49859 - 1086 WP_096226526.1 ATP-binding protein -
BN3560_RS00230 49872..51404 - 1533 WP_096226527.1 ribonuclease Y -
BN3560_RS00235 51723..52025 - 303 WP_096226528.1 XRE family transcriptional regulator Antitoxin
BN3560_RS00240 52029..52394 - 366 WP_096226529.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BN3560_RS00245 52476..53282 - 807 WP_096226530.1 RecX family transcriptional regulator -
BN3560_RS00250 53284..54342 - 1059 WP_087189757.1 recombinase RecA -
BN3560_RS00255 54628..55899 - 1272 WP_096226531.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
BN3560_RS00260 55909..57237 - 1329 WP_096226532.1 30S ribosomal protein S12 methylthiotransferase RimO -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-114)

Antitoxin

Cro/C1-type helix-turn-helix domain

(33-82)


Sequences

Toxin        


Download         Length: 122 a.a.        Molecular weight: 13929.99 Da        Isoelectric Point: 7.9099

>T293633 WP_096226529.1 NZ_LT900217:c52394-52029 [Gordonibacter urolithinfaciens]
MGWHVDIDLIKPWLDTQDLVTVSCIEAAIEELERKGPSLGRPLVDHIKDSEFCNMKELRPASPGRSEVRILFAFDPKRHA
IMLFAGDKSSGGRSREKWNGWYRSAIPLAEKRYREHLGRLE

Download         Length: 366 bp

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 11211.82 Da        Isoelectric Point: 8.9630

>AT293633 WP_096226528.1 NZ_LT900217:c52025-51723 [Gordonibacter urolithinfaciens]
MDIHEYAIKRGVTQEMRDQARRATQAKVDAYDLSQARKERDLTQSEVAAKMGVSQCRVSELEAGRLATMRVDTLSRYISS
LGGKLVISAEWPDKTIPLTI

Download         Length: 303 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References