Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemK-chpS/PRK09812-ChpS
Location 445151..445728 Replicon chromosome
Accession NZ_LT855380
Organism Pseudomonas viridiflava strain CFBP 1590 isolate E12-5

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag CFBP1590_RS02140 Protein ID WP_080665327.1
Coordinates 445402..445728 (+) Length 109 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID A0A5E7C1C9
Locus tag CFBP1590_RS02135 Protein ID WP_004880245.1
Coordinates 445151..445405 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CFBP1590_RS02115 440538..441929 + 1392 WP_088234402.1 heavy metal sensor histidine kinase -
CFBP1590_RS02120 442026..442427 + 402 WP_004880251.1 MAPEG family protein -
CFBP1590_RS02125 442763..443170 - 408 WP_043305551.1 DUF1090 domain-containing protein -
CFBP1590_RS02130 443225..444907 - 1683 WP_088234403.1 NAD-dependent DNA ligase LigB -
CFBP1590_RS02135 445151..445405 + 255 WP_004880245.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
CFBP1590_RS02140 445402..445728 + 327 WP_080665327.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
CFBP1590_RS02145 445673..446863 - 1191 WP_004880242.1 methionine adenosyltransferase -
CFBP1590_RS02150 446884..447879 - 996 WP_088234404.1 ArsR family transcriptional regulator -
CFBP1590_RS02155 448138..450135 + 1998 WP_029244141.1 transketolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-73)

Antitoxin

SpoVT-AbrB domain

(6-48)


Sequences

Toxin        


Download         Length: 109 a.a.        Molecular weight: 11913.60 Da        Isoelectric Point: 12.3548

>T293576 WP_080665327.1 NZ_LT855380:445402-445728 [Pseudomonas viridiflava]
VKQHGFNRADIVRISLNPTAGREQQRDFRPALVLTPAAYNVTGLAIVAPIIQGGDFARYSGFAVPLGGAGVPNKSPRRLT
SPGAFDDRRRITDRQQRAGRRRGRFFPK

Download         Length: 327 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9217.72 Da        Isoelectric Point: 4.6471

>AT293576 WP_004880245.1 NZ_LT855380:445151-445405 [Pseudomonas viridiflava]
MEVKIQQWGNSAAIRLPANVLKQMSLVIGDVLVLDVSSEVMTLKPAKARLHYQLADLMAQCDLNASEPEELAGWNAMQPI
GREA

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A5E7C1C9

References