Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 4196905..4197495 Replicon chromosome
Accession NZ_LT853885
Organism Xanthomonas fragariae strain PD5205

Toxin (Protein)


Gene name graT Uniprot ID A0A1Y6HPD3
Locus tag PD5205_RS19575 Protein ID WP_002803897.1
Coordinates 4197214..4197495 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name graA Uniprot ID -
Locus tag PD5205_RS19570 Protein ID WP_002803896.1
Coordinates 4196905..4197195 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PD5205_RS19545 4192410..4193378 - 969 WP_065975413.1 IS5 family transposase -
PD5205_RS19550 4193623..4194636 - 1014 WP_082244192.1 hypothetical protein -
PD5205_RS19555 4194817..4195419 - 603 WP_083215096.1 transposase -
PD5205_RS21045 4195525..4195827 - 303 WP_145954077.1 hypothetical protein -
PD5205_RS19560 4196029..4196361 + 333 WP_002803887.1 hypothetical protein -
PD5205_RS19570 4196905..4197195 - 291 WP_002803896.1 HigA family addiction module antidote protein Antitoxin
PD5205_RS19575 4197214..4197495 - 282 WP_002803897.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PD5205_RS19580 4197959..4200034 - 2076 WP_065975458.1 exodeoxyribonuclease V subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 4145492..4205567 60075


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(7-93)

Antitoxin

Toxin-antitoxin system, antidote protein, HigA

(1-94)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10897.61 Da        Isoelectric Point: 9.7550

>T293571 WP_002803897.1 NZ_LT853885:c4197495-4197214 [Xanthomonas fragariae]
MIKSIVDKEAEKIWVGERSRRLPADIQSVARRKLRMLNAAAHLDDLRIPPANRLEALKGERRGQYSIRINDQLRICFRWM
EGDVAEVEIVDYH

Download         Length: 282 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10528.25 Da        Isoelectric Point: 7.1667

>AT293571 WP_002803896.1 NZ_LT853885:c4197195-4196905 [Xanthomonas fragariae]
MTVLPNIHPGEILLEEFLEPMGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALCTTERFWLGLQADYELEQA
HRALGDLPSRIKRLAA

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1Y6HPD3

Antitoxin

Source ID Structure

References