293565

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 4236363..4236953 Replicon chromosome
Accession NZ_LT853882
Organism Xanthomonas fragariae strain PD885

Toxin (Protein)


Gene name graT Uniprot ID A0A1Y6HPD3
Locus tag PD885_RS19675 Protein ID WP_002803897.1
Coordinates 4236672..4236953 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name graA Uniprot ID -
Locus tag PD885_RS19670 Protein ID WP_002803896.1
Coordinates 4236363..4236653 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PD885_RS19645 4231868..4232836 - 969 WP_088057082.1 IS5 family transposase -
PD885_RS19650 4233081..4234094 - 1014 WP_082244192.1 hypothetical protein -
PD885_RS19655 4234230..4234877 - 648 WP_088057083.1 transposase -
PD885_RS21200 4234983..4235285 - 303 WP_145954077.1 hypothetical protein -
PD885_RS19660 4235487..4235819 + 333 WP_002803887.1 hypothetical protein -
PD885_RS19670 4236363..4236653 - 291 WP_002803896.1 HigA family addiction module antidote protein Antitoxin
PD885_RS19675 4236672..4236953 - 282 WP_002803897.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PD885_RS19680 4237417..4239492 - 2076 WP_065975458.1 exodeoxyribonuclease V subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(7-93)

Antitoxin

Toxin-antitoxin system, antidote protein, HigA

(1-94)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10897.61 Da        Isoelectric Point: 9.7550

>T293565 WP_002803897.1 NZ_LT853882:c4236953-4236672 [Xanthomonas fragariae]
MIKSIVDKEAEKIWVGERSRRLPADIQSVARRKLRMLNAAAHLDDLRIPPANRLEALKGERRGQYSIRINDQLRICFRWM
EGDVAEVEIVDYH

Download         Length: 282 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10528.25 Da        Isoelectric Point: 7.1667

>AT293565 WP_002803896.1 NZ_LT853882:c4236653-4236363 [Xanthomonas fragariae]
MTVLPNIHPGEILLEEFLEPMGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALCTTERFWLGLQADYELEQA
HRALGDLPSRIKRLAA

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1Y6HPD3

Antitoxin

Source ID Structure

References