Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 4209667..4210257 Replicon chromosome
Accession NZ_LT853880
Organism Xanthomonas fragariae strain NBC2815

Toxin (Protein)


Gene name graT Uniprot ID A0A1Y6HPD3
Locus tag NBC2815_RS19535 Protein ID WP_002803897.1
Coordinates 4209976..4210257 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name graA Uniprot ID -
Locus tag NBC2815_RS19530 Protein ID WP_002803896.1
Coordinates 4209667..4209957 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NBC2815_RS19510 4205665..4206678 - 1014 WP_088062318.1 hypothetical protein -
NBC2815_RS19515 4206814..4208181 - 1368 WP_088062671.1 IS5 family transposase -
NBC2815_RS20750 4208287..4208589 - 303 WP_134656642.1 hypothetical protein -
NBC2815_RS19520 4208791..4209123 + 333 WP_002803887.1 hypothetical protein -
NBC2815_RS19530 4209667..4209957 - 291 WP_002803896.1 HigA family addiction module antidote protein Antitoxin
NBC2815_RS19535 4209976..4210257 - 282 WP_002803897.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NBC2815_RS19540 4210721..4212796 - 2076 WP_088062320.1 exodeoxyribonuclease V subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(7-93)

Antitoxin

Toxin-antitoxin system, antidote protein, HigA

(1-94)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10897.61 Da        Isoelectric Point: 9.7550

>T293561 WP_002803897.1 NZ_LT853880:c4210257-4209976 [Xanthomonas fragariae]
MIKSIVDKEAEKIWVGERSRRLPADIQSVARRKLRMLNAAAHLDDLRIPPANRLEALKGERRGQYSIRINDQLRICFRWM
EGDVAEVEIVDYH

Download         Length: 282 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10528.25 Da        Isoelectric Point: 7.1667

>AT293561 WP_002803896.1 NZ_LT853880:c4209957-4209667 [Xanthomonas fragariae]
MTVLPNIHPGEILLEEFLEPMGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALCTTERFWLGLQADYELEQA
HRALGDLPSRIKRLAA

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1Y6HPD3

Antitoxin

Source ID Structure

References