Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 4209667..4210257 Replicon chromosome
Accession NZ_LT853880
Organism Xanthomonas fragariae strain NBC2815

Toxin (Protein)


Gene name graT Uniprot ID A0A1Y6HPD3
Locus tag NBC2815_RS19535 Protein ID WP_002803897.1
Coordinates 4209976..4210257 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name graA Uniprot ID -
Locus tag NBC2815_RS19530 Protein ID WP_002803896.1
Coordinates 4209667..4209957 (-) Length 97 a.a.

Genomic Context

NBC2815_RS19520NBC2815_RS19510NBC2815_RS19515NBC2815_RS20750NBC2815_RS19530NBC2815_RS19535NBC2815_RS19540
Location: 4208791..4209123 (333 bp)
Type: Others
Protein ID: WP_002803887.1
Location: 4205665..4206678 (1014 bp)
Type: Others
Protein ID: WP_088062318.1
Location: 4206814..4208181 (1368 bp)
Type: Others
Protein ID: WP_088062671.1
Location: 4208287..4208589 (303 bp)
Type: Others
Protein ID: WP_134656642.1
Location: 4209667..4209957 (291 bp)
Type: Antitoxin
Protein ID: WP_002803896.1
Location: 4209976..4210257 (282 bp)
Type: Toxin
Protein ID: WP_002803897.1
Location: 4210721..4212796 (2076 bp)
Type: Others
Protein ID: WP_088062320.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
NBC2815_RS195104205665..4206678-1014WP_088062318.1hypothetical protein-
NBC2815_RS195154206814..4208181-1368WP_088062671.1IS5 family transposase-
NBC2815_RS207504208287..4208589-303WP_134656642.1hypothetical protein-
NBC2815_RS195204208791..4209123+333WP_002803887.1hypothetical protein-
NBC2815_RS195304209667..4209957-291WP_002803896.1HigA family addiction module antidote proteinAntitoxin
NBC2815_RS195354209976..4210257-282WP_002803897.1type II toxin-antitoxin system RelE/ParE family toxinToxin
NBC2815_RS195404210721..4212796-2076WP_088062320.1exodeoxyribonuclease V subunit alpha-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(7-93)

Antitoxin

Toxin-antitoxin system, antidote protein, HigA

(1-94)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10897.61 Da        Isoelectric Point: 9.7550

>T293561 WP_002803897.1 NZ_LT853880:c4210257-4209976 [Xanthomonas fragariae]
MIKSIVDKEAEKIWVGERSRRLPADIQSVARRKLRMLNAAAHLDDLRIPPANRLEALKGERRGQYSIRINDQLRICFRWM
EGDVAEVEIVDYH

Download         Length: 282 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10528.25 Da        Isoelectric Point: 7.1667

>AT293561 WP_002803896.1 NZ_LT853880:c4209957-4209667 [Xanthomonas fragariae]
MTVLPNIHPGEILLEEFLEPMGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALCTTERFWLGLQADYELEQA
HRALGDLPSRIKRLAA

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A1Y6HPD3

Antitoxin

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Source
ID
Structure
No matching records found

References