Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | DinJ-YafQ (relBE)/YafQ-DinJ |
| Location | 113920..114454 | Replicon | chromosome |
| Accession | NZ_LT706985 | ||
| Organism | Propionimicrobium sp. Marseille-P3275 strain Marseille-P3275T | ||
Toxin (Protein)
| Gene name | yafQ | Uniprot ID | - |
| Locus tag | CZ356_RS00580 | Protein ID | WP_076387812.1 |
| Coordinates | 114170..114454 (+) | Length | 95 a.a. |
Antitoxin (Protein)
| Gene name | dinJ | Uniprot ID | - |
| Locus tag | CZ356_RS00575 | Protein ID | WP_076389689.1 |
| Coordinates | 113920..114183 (+) | Length | 88 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CZ356_RS00545 | 109552..109815 | + | 264 | WP_076387806.1 | immunity 17 family protein | - |
| CZ356_RS00550 | 109802..110470 | + | 669 | WP_197684197.1 | DUF4304 domain-containing protein | - |
| CZ356_RS00555 | 110610..111848 | + | 1239 | WP_076387808.1 | DUF695 domain-containing protein | - |
| CZ356_RS00560 | 111874..112311 | + | 438 | WP_197684198.1 | hypothetical protein | - |
| CZ356_RS00565 | 112586..112864 | - | 279 | WP_057002045.1 | hypothetical protein | - |
| CZ356_RS00570 | 113073..113519 | - | 447 | WP_162272852.1 | hypothetical protein | - |
| CZ356_RS00575 | 113920..114183 | + | 264 | WP_076389689.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
| CZ356_RS00580 | 114170..114454 | + | 285 | WP_076387812.1 | type II toxin-antitoxin system YafQ family toxin | Toxin |
| CZ356_RS00585 | 114660..115040 | + | 381 | WP_076387814.1 | hypothetical protein | - |
| CZ356_RS00590 | 115131..116336 | + | 1206 | WP_076389690.1 | SPFH domain-containing protein | - |
| CZ356_RS00595 | 116558..117763 | + | 1206 | WP_076387816.1 | ATP-binding protein | - |
| CZ356_RS00600 | 117780..118754 | + | 975 | WP_076387818.1 | TPM domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 95 a.a. Molecular weight: 11058.60 Da Isoelectric Point: 8.8752
>T293447 WP_076387812.1 NZ_LT706985:114170-114454 [Propionimicrobium sp. Marseille-P3275]
MRLTSVFRTYQFKRDAKAPFKKNYDAQKLASAVEALLAQDRDGLCTHYRDHALQGSWKGYREIHIEADWLLIYRVERSEL
LLVLTRTGSHDDLF
MRLTSVFRTYQFKRDAKAPFKKNYDAQKLASAVEALLAQDRDGLCTHYRDHALQGSWKGYREIHIEADWLLIYRVERSEL
LLVLTRTGSHDDLF
Download Length: 285 bp
Antitoxin
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|