Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2186324..2186587 Replicon chromosome
Accession NZ_LT671859
Organism Staphylococcus aureus isolate Clinical isolate

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag EDCC5055_RS11450 Protein ID WP_001802298.1
Coordinates 2186483..2186587 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2186324..2186488 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EDCC5055_RS11430 2182507..2183172 - 666 WP_001024094.1 SDR family oxidoreductase -
EDCC5055_RS11435 2183324..2183644 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
EDCC5055_RS11440 2183646..2184626 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
EDCC5055_RS11445 2184892..2185983 + 1092 WP_000495671.1 lytic regulatory protein -
- 2186324..2186488 + 165 - - Antitoxin
EDCC5055_RS11450 2186483..2186587 - 105 WP_001802298.1 hypothetical protein Toxin
EDCC5055_RS15040 2186748..2187231 - 484 Protein_2100 recombinase family protein -
EDCC5055_RS11460 2187274..2188410 - 1137 WP_000115564.1 SAP domain-containing protein -
EDCC5055_RS11465 2188699..2188791 + 93 WP_001790138.1 hypothetical protein -
EDCC5055_RS11470 2189496..2190353 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
EDCC5055_RS11475 2190421..2191203 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T293424 WP_001802298.1 NZ_LT671859:c2186587-2186483 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 165 bp

>AT293424 NZ_LT671859:2186324-2186488 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References