Detailed information of TA system TA293417

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1848827..1849009
• Replicon: chromosome
• Accession: NZ_LT671859
• Organism: Staphylococcus aureus isolate Clinical isolate

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: EDCC5055_RS15015
• Protein ID: WP_001801861.1
• Coordinates: 1848827..1848922 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1848950..1849009 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EDCC5055_RS09265	1844488..1845114	+	627	WP_000669046.1	hypothetical protein	-
EDCC5055_RS09270	1845155..1845499	+	345	WP_000627551.1	DUF3969 family protein	-
EDCC5055_RS09275	1845597..1846147	+	551	Protein_1733	hypothetical protein	-
EDCC5055_RS09280	1846365..1847006	-	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
EDCC5055_RS09285	1847120..1847305	-	186	WP_000809857.1	hypothetical protein	-
EDCC5055_RS09290	1847307..1847483	-	177	WP_000375476.1	hypothetical protein	-
EDCC5055_RS09295	1847494..1847877	-	384	WP_000070811.1	hypothetical protein	-
EDCC5055_RS09310	1848481..1848624	-	144	WP_001549059.1	transposase	-
EDCC5055_RS15015	1848827..1848922	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1848950..1849009	-	60	-	-	Antitoxin
EDCC5055_RS09315	1849045..1849146	+	102	WP_001791893.1	hypothetical protein	-
EDCC5055_RS09320	1849124..1849300	-	177	Protein_1741	transposase	-
EDCC5055_RS09325	1849494..1849871	-	378	WP_001037045.1	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1841928..1868925	26997

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T293417 WP_001801861.1 NZ_LT671859:1848827-1848922 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

Antitoxin

Nucleotide

• Length: 60 bp

>AT293417 NZ_LT671859:c1849009-1848950 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin