Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DinJ-YafQ (relBE)/YafQ-RelB
Location 2653934..2654467 Replicon chromosome
Accession NZ_LT630450
Organism Desulfovibrio piger strain FI11049 isolate FI11049

Toxin (Protein)


Gene name yafQ Uniprot ID -
Locus tag DESPIGER_RS11825 Protein ID WP_072337211.1
Coordinates 2654195..2654467 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID A0A1K1LHX6
Locus tag DESPIGER_RS11820 Protein ID WP_072337209.1
Coordinates 2653934..2654194 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DESPIGER_RS11800 2649747..2650793 - 1047 WP_072337201.1 type IV secretory system conjugative DNA transfer family protein -
DESPIGER_RS11805 2650790..2651260 - 471 WP_072337203.1 DotD/TraH family lipoprotein -
DESPIGER_RS11810 2651303..2651746 - 444 WP_072337205.1 hypothetical protein -
DESPIGER_RS11815 2651752..2653851 - 2100 WP_072337207.1 DotA/TraY family protein -
DESPIGER_RS11820 2653934..2654194 + 261 WP_072337209.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
DESPIGER_RS11825 2654195..2654467 + 273 WP_072337211.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
DESPIGER_RS11830 2654486..2655586 - 1101 WP_072337213.1 hypothetical protein -
DESPIGER_RS11840 2658561..2659271 - 711 WP_072337217.1 DotI/IcmL/TraM family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 2627314..2666834 39520


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-88)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-84)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10872.55 Da        Isoelectric Point: 8.5040

>T293400 WP_072337211.1 NZ_LT630450:2654195-2654467 [Desulfovibrio piger]
VRNSTFTAQFRRDLRKVEHRGYDMQKLKTIIMLLLNEEPLPKHCRDHALKGEWKPYRELHIEPDWLLVYKVSENECVFYR
TGTHADLFSL

Download         Length: 273 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9578.97 Da        Isoelectric Point: 5.1356

>AT293400 WP_072337209.1 NZ_LT630450:2653934-2654194 [Desulfovibrio piger]
MPANDYVRARIDPAIKNEAAAVLATMGLTVSDLCRMALARVAHEKRLPFSDDIPNALTRETIEKAERGEEIFHAKDAEDL
FRQLGI

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A1K1LHX6

References