Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2164235..2164451 Replicon chromosome
Accession NZ_LT615218
Organism Staphylococcus aureus strain AUS0325

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag BQ3358_RS11025 Protein ID WP_001802298.1
Coordinates 2164347..2164451 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2164235..2164290 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BQ3358_RS11005 2160441..2161106 - 666 WP_001024089.1 SDR family oxidoreductase -
BQ3358_RS11010 2161258..2161578 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
BQ3358_RS11015 2161580..2162557 + 978 WP_000019733.1 CDF family zinc efflux transporter CzrB -
BQ3358_RS11020 2162823..2163914 + 1092 WP_000495669.1 hypothetical protein -
- 2164235..2164290 + 56 - - Antitoxin
BQ3358_RS11025 2164347..2164451 - 105 WP_001802298.1 hypothetical protein Toxin
BQ3358_RS14545 2165131..2165289 + 159 WP_001792784.1 hypothetical protein -
BQ3358_RS11030 2165947..2166804 - 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
BQ3358_RS11035 2166872..2167654 - 783 WP_000908185.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T293315 WP_001802298.1 NZ_LT615218:c2164451-2164347 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 56 bp

>AT293315 NZ_LT615218:2164235-2164290 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References