293148

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 665870..666686 Replicon chromosome
Accession NZ_LT556085
Organism Citrobacter amalonaticus strain 92

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag CITRO92_RS03275 Protein ID WP_109739561.1
Coordinates 665870..666346 (-) Length 159 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID A0A3Q8DNJ3
Locus tag CITRO92_RS03280 Protein ID WP_042999108.1
Coordinates 666351..666686 (-) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CITRO92_RS03255 660975..661718 - 744 WP_044264050.1 molecular chaperone -
CITRO92_RS03260 661761..664235 - 2475 WP_044257386.1 fimbria/pilus outer membrane usher protein -
CITRO92_RS03265 664299..664748 - 450 WP_086513030.1 type 1 fimbrial protein -
CITRO92_RS03270 664916..665446 - 531 WP_042999110.1 type 1 fimbrial protein -
CITRO92_RS03275 665870..666346 - 477 WP_109739561.1 type II toxin-antitoxin system YhaV family toxin Toxin
CITRO92_RS03280 666351..666686 - 336 WP_042999108.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
CITRO92_RS03285 666901..667437 - 537 WP_042999107.1 ferredoxin-type protein NapF -
CITRO92_RS03290 667434..668030 - 597 WP_042999106.1 molecular chaperone -
CITRO92_RS03295 668075..668848 - 774 WP_044327723.1 dimethyl sulfoxide reductase anchor subunit -
CITRO92_RS03300 668841..669467 - 627 WP_109739562.1 dimethylsulfoxide reductase subunit B -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(12-150)

Antitoxin

PrlF antitoxin

(15-110)


Sequences

Toxin        


Download         Length: 159 a.a.        Molecular weight: 18170.78 Da        Isoelectric Point: 8.2616

>T293148 WP_109739561.1 NZ_LT556085:c666346-665870 [Citrobacter amalonaticus]
MDFPTWLNGWTIYAHPCFIDQYNALVARVEDLKHRFPDPIVFQKKKETMVLAHLLKSIANITHEPRASVYRPGDSIGKAY
TDWSRAKFGGGRYRLFFRYSLESKIIVIAWVNDEGSLRTCGSKTDAYKIFGKMLDEGNPPDDWLSLLQACQNDGKEHL

Download         Length: 477 bp

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12505.83 Da        Isoelectric Point: 4.1876

>AT293148 WP_042999108.1 NZ_LT556085:c666686-666351 [Citrobacter amalonaticus]
MFAYVRSEDIAIEADSKLTERHQTTIPASIRDALHLRSGDRIHYTLLSTGEVLLSKYSEATEDGVMRSFLDFLSQDVANN
PQTLKKLDLSRGYELVDGIDVNLDDEISDED

Download         Length: 336 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A3Q8DNJ3

References