Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 1147191..1148007 Replicon chromosome
Accession NZ_LT556084
Organism Citrobacter amalonaticus strain 86

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag CITRO86_RS05590 Protein ID WP_109739561.1
Coordinates 1147531..1148007 (+) Length 159 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID A0A3Q8DNJ3
Locus tag CITRO86_RS05585 Protein ID WP_042999108.1
Coordinates 1147191..1147526 (+) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CITRO86_RS05565 1144410..1145036 + 627 WP_109739562.1 dimethylsulfoxide reductase subunit B -
CITRO86_RS05570 1145029..1145802 + 774 WP_044327723.1 dimethyl sulfoxide reductase anchor subunit -
CITRO86_RS05575 1145847..1146443 + 597 WP_042999106.1 molecular chaperone -
CITRO86_RS05580 1146440..1146976 + 537 WP_042999107.1 ferredoxin-type protein NapF -
CITRO86_RS05585 1147191..1147526 + 336 WP_042999108.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
CITRO86_RS05590 1147531..1148007 + 477 WP_109739561.1 type II toxin-antitoxin system YhaV family toxin Toxin
CITRO86_RS05595 1148431..1148961 + 531 WP_042999110.1 type 1 fimbrial protein -
CITRO86_RS05600 1149129..1149578 + 450 WP_086513030.1 type 1 fimbrial protein -
CITRO86_RS05605 1149642..1152116 + 2475 WP_044257386.1 fimbria/pilus outer membrane usher protein -
CITRO86_RS05610 1152159..1152902 + 744 WP_044264050.1 molecular chaperone -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(12-150)

Antitoxin

PrlF antitoxin

(15-110)


Sequences

Toxin        


Download         Length: 159 a.a.        Molecular weight: 18170.78 Da        Isoelectric Point: 8.2616

>T293133 WP_109739561.1 NZ_LT556084:1147531-1148007 [Citrobacter amalonaticus]
MDFPTWLNGWTIYAHPCFIDQYNALVARVEDLKHRFPDPIVFQKKKETMVLAHLLKSIANITHEPRASVYRPGDSIGKAY
TDWSRAKFGGGRYRLFFRYSLESKIIVIAWVNDEGSLRTCGSKTDAYKIFGKMLDEGNPPDDWLSLLQACQNDGKEHL

Download         Length: 477 bp

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12505.83 Da        Isoelectric Point: 4.1876

>AT293133 WP_042999108.1 NZ_LT556084:1147191-1147526 [Citrobacter amalonaticus]
MFAYVRSEDIAIEADSKLTERHQTTIPASIRDALHLRSGDRIHYTLLSTGEVLLSKYSEATEDGVMRSFLDFLSQDVANN
PQTLKKLDLSRGYELVDGIDVNLDDEISDED

Download         Length: 336 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A3Q8DNJ3

References