Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 1147191..1148007 Replicon chromosome
Accession NZ_LT556084
Organism Citrobacter amalonaticus strain 86

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag CITRO86_RS05590 Protein ID WP_109739561.1
Coordinates 1147531..1148007 (+) Length 159 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID A0A3Q8DNJ3
Locus tag CITRO86_RS05585 Protein ID WP_042999108.1
Coordinates 1147191..1147526 (+) Length 112 a.a.

Genomic Context

CITRO86_RS05565CITRO86_RS05570CITRO86_RS05575CITRO86_RS05580CITRO86_RS05585CITRO86_RS05590CITRO86_RS05595CITRO86_RS05600CITRO86_RS05605CITRO86_RS05610
Location: 1144410..1145036 (627 bp)
Type: Others
Protein ID: WP_109739562.1
Location: 1145029..1145802 (774 bp)
Type: Others
Protein ID: WP_044327723.1
Location: 1145847..1146443 (597 bp)
Type: Others
Protein ID: WP_042999106.1
Location: 1146440..1146976 (537 bp)
Type: Others
Protein ID: WP_042999107.1
Location: 1147191..1147526 (336 bp)
Type: Antitoxin
Protein ID: WP_042999108.1
Location: 1147531..1148007 (477 bp)
Type: Toxin
Protein ID: WP_109739561.1
Location: 1148431..1148961 (531 bp)
Type: Others
Protein ID: WP_042999110.1
Location: 1149129..1149578 (450 bp)
Type: Others
Protein ID: WP_086513030.1
Location: 1149642..1152116 (2475 bp)
Type: Others
Protein ID: WP_044257386.1
Location: 1152159..1152902 (744 bp)
Type: Others
Protein ID: WP_044264050.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
CITRO86_RS055651144410..1145036+627WP_109739562.1dimethylsulfoxide reductase subunit B-
CITRO86_RS055701145029..1145802+774WP_044327723.1dimethyl sulfoxide reductase anchor subunit-
CITRO86_RS055751145847..1146443+597WP_042999106.1molecular chaperone-
CITRO86_RS055801146440..1146976+537WP_042999107.1ferredoxin-type protein NapF-
CITRO86_RS055851147191..1147526+336WP_042999108.1type II toxin-antitoxin system PrlF family antitoxinAntitoxin
CITRO86_RS055901147531..1148007+477WP_109739561.1type II toxin-antitoxin system YhaV family toxinToxin
CITRO86_RS055951148431..1148961+531WP_042999110.1type 1 fimbrial protein-
CITRO86_RS056001149129..1149578+450WP_086513030.1type 1 fimbrial protein-
CITRO86_RS056051149642..1152116+2475WP_044257386.1fimbria/pilus outer membrane usher protein-
CITRO86_RS056101152159..1152902+744WP_044264050.1molecular chaperone-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(12-150)

Antitoxin

PrlF antitoxin

(15-110)


Sequences

Toxin        


Download         Length: 159 a.a.        Molecular weight: 18170.78 Da        Isoelectric Point: 8.2616

>T293133 WP_109739561.1 NZ_LT556084:1147531-1148007 [Citrobacter amalonaticus]
MDFPTWLNGWTIYAHPCFIDQYNALVARVEDLKHRFPDPIVFQKKKETMVLAHLLKSIANITHEPRASVYRPGDSIGKAY
TDWSRAKFGGGRYRLFFRYSLESKIIVIAWVNDEGSLRTCGSKTDAYKIFGKMLDEGNPPDDWLSLLQACQNDGKEHL

Download         Length: 477 bp

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12505.83 Da        Isoelectric Point: 4.1876

>AT293133 WP_042999108.1 NZ_LT556084:1147191-1147526 [Citrobacter amalonaticus]
MFAYVRSEDIAIEADSKLTERHQTTIPASIRDALHLRSGDRIHYTLLSTGEVLLSKYSEATEDGVMRSFLDFLSQDVANN
PQTLKKLDLSRGYELVDGIDVNLDDEISDED

Download         Length: 336 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A3Q8DNJ3

References