Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2229935..2230151 Replicon chromosome
Accession NZ_LT009690
Organism Staphylococcus aureus strain NZAK3

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag NZAK3_RS11370 Protein ID WP_001802298.1
Coordinates 2230047..2230151 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2229935..2229990 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NZAK3_RS11350 2226141..2226806 - 666 WP_001024095.1 SDR family oxidoreductase -
NZAK3_RS11355 2226958..2227278 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
NZAK3_RS11360 2227280..2228257 + 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
NZAK3_RS11365 2228523..2229614 + 1092 WP_000495669.1 hypothetical protein -
- 2229935..2229990 + 56 - - Antitoxin
NZAK3_RS11370 2230047..2230151 - 105 WP_001802298.1 hypothetical protein Toxin
NZAK3_RS15000 2230831..2230989 + 159 WP_001792784.1 hypothetical protein -
NZAK3_RS11375 2231647..2232504 - 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
NZAK3_RS11380 2232572..2233354 - 783 WP_000908182.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T293108 WP_001802298.1 NZ_LT009690:c2230151-2230047 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 56 bp

>AT293108 NZ_LT009690:2229935-2229990 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References