Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 2009453..2010042 Replicon chromosome
Accession NZ_LS999833
Organism Lentilitoribacter sp. Alg239-R112

Toxin (Protein)


Gene name graT Uniprot ID -
Locus tag G3W54_RS09980 Protein ID WP_162652913.1
Coordinates 2009764..2010042 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag G3W54_RS09975 Protein ID WP_162652912.1
Coordinates 2009453..2009746 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G3W54_RS09955 2005524..2006747 - 1224 WP_162652910.1 O-antigen ligase family protein -
G3W54_RS09960 2006968..2008476 + 1509 WP_162652911.1 GumC family protein -
G3W54_RS19195 2008661..2008828 + 168 WP_197742819.1 transposase -
G3W54_RS19200 2009173..2009292 + 120 Protein_1979 tyrosine-type recombinase/integrase -
G3W54_RS09975 2009453..2009746 - 294 WP_162652912.1 HigA family addiction module antidote protein Antitoxin
G3W54_RS09980 2009764..2010042 - 279 WP_162652913.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
G3W54_RS09985 2010166..2010768 - 603 WP_162653647.1 histidine phosphatase family protein -
G3W54_RS09990 2010765..2011823 - 1059 WP_162652914.1 ABC transporter ATP-binding protein -
G3W54_RS09995 2011833..2013578 - 1746 WP_162652915.1 iron ABC transporter permease -
G3W54_RS10000 2013663..2014784 - 1122 WP_162652916.1 ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 2008661..2008828 167


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(4-92)

Antitoxin

Cro/C1-type helix-turn-helix domain

(9-66)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10737.04 Da        Isoelectric Point: 5.1356

>T293097 WP_162652913.1 NZ_LS999833:c2010042-2009764 [Lentilitoribacter sp. Alg239-R112]
MIKSYRDKKTSVFANGEFVRIFQGFSRQAEKRLEILDAAEITGDLTVLPSNRFEALSGDRVGQFSIRINQQWHICFEWRD
DGPENVEIVDYH

Download         Length: 279 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10980.60 Da        Isoelectric Point: 8.6583

>AT293097 WP_162652912.1 NZ_LS999833:c2009746-2009453 [Lentilitoribacter sp. Alg239-R112]
MSRTPIHPGEILKDELEEIGISAAELARQLRVPENRMSEVMRGRRNITADTALRLGKWFGSSAVFWMNLQKNYELRKAEQ
EIGADIDQIKTRVAVAG

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References