Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | yefM-yoeB (relBE)/YoeB-YefM |
Location | 1960235..1960737 | Replicon | chromosome |
Accession | NZ_LS992190 | ||
Organism | Escherichia coli isolate Escherichia coli str. TO148 |
Toxin (Protein)
Gene name | yoeB | Uniprot ID | E2QNP2 |
Locus tag | ECTO148_RS09380 | Protein ID | WP_000767819.1 |
Coordinates | 1960483..1960737 (+) | Length | 85 a.a. |
Antitoxin (Protein)
Gene name | yefM | Uniprot ID | E2QNP3 |
Locus tag | ECTO148_RS09375 | Protein ID | WP_001259253.1 |
Coordinates | 1960235..1960486 (+) | Length | 84 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
ECTO148_RS09345 | 1955413..1956480 | - | 1068 | WP_000080057.1 | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | - |
ECTO148_RS09350 | 1956480..1957550 | - | 1071 | WP_000108967.1 | histidinol-phosphate transaminase | - |
ECTO148_RS09355 | 1957547..1958851 | - | 1305 | WP_001296211.1 | histidinol dehydrogenase | - |
ECTO148_RS09360 | 1958857..1959756 | - | 900 | WP_000131782.1 | ATP phosphoribosyltransferase | - |
ECTO148_RS09365 | 1959902..1959952 | - | 51 | WP_001364200.1 | his operon leader peptide | - |
ECTO148_RS09375 | 1960235..1960486 | + | 252 | WP_001259253.1 | YoeB-YefM toxin-antitoxin system antitoxin YefM | Antitoxin |
ECTO148_RS09380 | 1960483..1960737 | + | 255 | WP_000767819.1 | type II toxin-antitoxin system mRNA interferase toxin YoeB | Toxin |
ECTO148_RS09385 | 1960820..1961644 | + | 825 | WP_000754737.1 | SDR family oxidoreductase | - |
ECTO148_RS09390 | 1961690..1962619 | + | 930 | WP_000803366.1 | LysR family transcriptional regulator | - |
ECTO148_RS09395 | 1962834..1962896 | + | 63 | WP_010723108.1 | membrane protein YoeI | - |
ECTO148_RS09400 | 1962886..1964244 | + | 1359 | WP_000019194.1 | putrescine/proton symporter PlaP | - |
ECTO148_RS09410 | 1964461..1964919 | + | 459 | WP_001531805.1 | IS200/IS605-like element IS200C family transposase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | flank | IS/Tn | - | - | 1964461..1964919 | 458 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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