Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 3330019..3331351 Replicon chromosome
Accession NZ_LS483499
Organism Tatumella ptyseos strain NCTC11468

Toxin (Protein)


Gene name HipT Uniprot ID A0A085JMC7
Locus tag DQM83_RS16060 Protein ID WP_029990713.1
Coordinates 3330019..3331047 (-) Length 343 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID -
Locus tag DQM83_RS16065 Protein ID WP_025904086.1
Coordinates 3331037..3331351 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQM83_RS16045 3326370..3327212 + 843 WP_025904090.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
DQM83_RS16050 3327217..3328125 - 909 WP_025904089.1 ribonuclease Z -
DQM83_RS16055 3328322..3329674 + 1353 WP_025904088.1 glutathione-disulfide reductase -
DQM83_RS16060 3330019..3331047 - 1029 WP_029990713.1 HipA domain-containing protein Toxin
DQM83_RS16065 3331037..3331351 - 315 WP_025904086.1 HipA N-terminal domain-containing protein Antitoxin
DQM83_RS16070 3331344..3331565 - 222 WP_111678695.1 hypothetical protein -
DQM83_RS16075 3332274..3333604 - 1331 Protein_3044 aspartate aminotransferase family protein -
DQM83_RS16085 3333959..3335269 - 1311 WP_029990718.1 CitMHS family transporter -
DQM83_RS16090 3335719..3335874 - 156 WP_071780125.1 DUF3950 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(58-301)

Antitoxin

HipA, N-terminal subdomain 1

(7-98)


Sequences

Toxin        


Download         Length: 343 a.a.        Molecular weight: 38278.75 Da        Isoelectric Point: 5.1470

>T292672 WP_029990713.1 NZ_LS483499:c3331047-3330019 [Tatumella ptyseos]
MTYERCLIGLHPLKQKEKAAGRCVKESQALFGKDSDIYQLPFTRSDFVRTQPAKQKGMSISGVQPKLSLRMSDQGQLEVT
PTSGEYILKPSPEQFPGLAENEHAIMCCMKELDFDIPGFGLIPFAGEDGQERAELAFIIERYDRHGSVKVHQEQLDGAMS
VNDKYGLNAVGQPAISYEQAARFLVTNVDGSLQSKREIFKRVVCAYMLGNNDFHLRNIGIIHPANGPLLLAPVYDFVSVV
PYHESFGSTLALPLLAREECDQSLADGLDSGIGEYIGYDFLEFARGIGLNENLAKKELDKLLLAQEKIFGIINDSYMSDE
HKEKVTQYINRRMMLLDMTDKP

Download         Length: 1029 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11769.40 Da        Isoelectric Point: 5.4854

>AT292672 WP_025904086.1 NZ_LS483499:c3331351-3331037 [Tatumella ptyseos]
MHRNVMVYLHSTLAGMLTQSDKGYTFSYQPDYQGRAISLSLPLNGGPFFSEVLHPFFQGLAPEGWLRKRYSEIQHLDEKD
LLGMLIANNQDLLGAITLELNNDV

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A085JMC7

Antitoxin

Source ID Structure

References