Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 3243806..3244308 Replicon chromosome
Accession NZ_LS483499
Organism Tatumella ptyseos strain NCTC11468

Toxin (Protein)


Gene name yoeB Uniprot ID A0A085JM02
Locus tag DQM83_RS15640 Protein ID WP_025904159.1
Coordinates 3243806..3244060 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A085JM01
Locus tag DQM83_RS15645 Protein ID WP_029991719.1
Coordinates 3244057..3244308 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQM83_RS15630 3239777..3242038 + 2262 WP_029991717.1 hypothetical protein -
DQM83_RS15635 3242042..3242902 + 861 WP_029991718.1 SUMF1/EgtB/PvdO family nonheme iron enzyme -
DQM83_RS17585 3243481..3243645 - 165 WP_156097538.1 hypothetical protein -
DQM83_RS15640 3243806..3244060 - 255 WP_025904159.1 Txe/YoeB family addiction module toxin Toxin
DQM83_RS15645 3244057..3244308 - 252 WP_029991719.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
DQM83_RS15655 3245428..3246033 - 606 WP_029991720.1 TetR/AcrR family transcriptional regulator -
DQM83_RS15660 3246110..3246922 + 813 WP_029991721.1 SDR family NAD(P)-dependent oxidoreductase -
DQM83_RS15695 3247889..3248629 - 741 WP_029991722.1 lipopolysaccharide N-acetylmannosaminouronosyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9985.36 Da        Isoelectric Point: 8.8103

>T292671 WP_025904159.1 NZ_LS483499:c3244060-3243806 [Tatumella ptyseos]
VKLIWSEEAWEDYLYWQNADKKTVKKINELIKDASRTPFEGKGKPEPLKYNLAGFWSRRITAEHRFVYAVSDDSLLIASC
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9349.57 Da        Isoelectric Point: 4.7707

>AT292671 WP_029991719.1 NZ_LS483499:c3244308-3244057 [Tatumella ptyseos]
MKAVSYSEARQNLSATMIQTVEDRSPILITRQNGESCVLMSLEEFNSLEETAYLLRSPKNARRLMDSVDSLKNGNGVERN
VIE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A085JM02

Antitoxin

Source ID Structure
AlphaFold DB A0A085JM01

References