Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2305470..2305686 Replicon chromosome
Accession NZ_LS483484
Organism Staphylococcus aureus strain NCTC13277

Toxin (Protein)


Gene name SprG3 Uniprot ID -
Locus tag DQL77_RS11905 Protein ID WP_073392962.1
Coordinates 2305582..2305686 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2305470..2305525 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQL77_RS11885 2300563..2300883 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
DQL77_RS11890 2300885..2301865 + 981 WP_000019741.1 CDF family zinc efflux transporter CzrB -
DQL77_RS11895 2302131..2303222 + 1092 WP_000495684.1 hypothetical protein -
DQL77_RS11900 2303510..2305156 + 1647 WP_000277709.1 IS1182-like element ISSau3 family transposase -
- 2305470..2305525 + 56 - - Antitoxin
DQL77_RS11905 2305582..2305686 - 105 WP_073392962.1 hypothetical protein Toxin
DQL77_RS11915 2306366..2306524 + 159 WP_001792784.1 hypothetical protein -
DQL77_RS11925 2307183..2308040 - 858 WP_000370937.1 Cof-type HAD-IIB family hydrolase -
DQL77_RS11930 2308108..2308890 - 783 WP_000908186.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 2303510..2305156 1646


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3920.80 Da        Isoelectric Point: 5.5724

>T292636 WP_073392962.1 NZ_LS483484:c2305686-2305582 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 56 bp

>AT292636 NZ_LS483484:2305470-2305525 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References