Detailed information of TA system TA292625

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 1046279..1046528
• Replicon: chromosome
• Accession: NZ_LS483484
• Organism: Staphylococcus aureus strain NCTC13277

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: DQL77_RS05190
• Protein ID: WP_000623369.1
• Coordinates: 1046279..1046386 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF2
Locus tag	-
Coordinates	1046381..1046528 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DQL77_RS05165	1042952..1043521	-	570	WP_000287265.1	competence protein ComK	-
DQL77_RS05170	1043731..1043949	+	219	WP_000876825.1	IDEAL domain-containing protein	-
DQL77_RS05175	1044030..1045016	-	987	WP_000668820.1	lipoate--protein ligase	-
DQL77_RS05180	1045215..1045391	+	177	WP_000214898.1	YkvS family protein	-
DQL77_RS05185	1045406..1046008	+	603	WP_001033867.1	CPBP family intramembrane metalloprotease	-
DQL77_RS05190	1046279..1046386	+	108	WP_000623369.1	putative holin-like toxin	Toxin
-	1046381..1046528	-	148	-	-	Antitoxin
DQL77_RS05195	1046925..1047026	+	102	WP_001790623.1	hypothetical protein	-
DQL77_RS05200	1047036..1047308	+	273	WP_001794574.1	lactococcin 972 family bacteriocin	-
DQL77_RS05205	1047352..1049316	+	1965	WP_000870819.1	bacteriocin-associated integral membrane family protein	-
DQL77_RS05210	1049319..1049639	+	321	WP_000873929.1	YxeA family protein	-
DQL77_RS05215	1049636..1050277	+	642	WP_000571191.1	ABC transporter ATP-binding protein	-
DQL77_RS05220	1050365..1050655	-	291	WP_001791476.1	hypothetical protein	-
DQL77_RS05225	1050996..1051283	+	288	WP_000410718.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3801.69 Da
• Isoelectric Point: 10.8004

>T292625 WP_000623369.1 NZ_LS483484:1046279-1046386 [Staphylococcus aureus]
VISIANALHLMLSFGMFIVTFIGVVVAIINLNNKK

Nucleotide

• Length: 108 bp

Antitoxin

Nucleotide

• Length: 148 bp

>AT292625 NZ_LS483484:c1046528-1046381 [Staphylococcus aureus]
CAATTAAATAAAAGATATGTTACTATAAAAATGTAAAAAGACGACATGCAGGAACATGTCGCCTAATGAGCCCGTTAAAA
AGACGGTGACTAAATGAGATTTTCTTTAACCATCATTCGTTGTCAAAGTTTTGAAATGATGGTTATTT

Structures

Antitoxin