Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-VapI
Location 1692111..1692700 Replicon chromosome
Accession NZ_LS483460
Organism Corynebacterium minutissimum strain NCTC10288

Toxin (Protein)


Gene name graT Uniprot ID -
Locus tag DQN65_RS07725 Protein ID WP_082013920.1
Coordinates 1692419..1692700 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag DQN65_RS07720 Protein ID WP_039674786.1
Coordinates 1692111..1692410 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQN65_RS07690 1687630..1688352 + 723 WP_039674796.1 hypothetical protein -
DQN65_RS07695 1688352..1688888 + 537 WP_039674795.1 DUF402 domain-containing protein -
DQN65_RS07700 1688933..1689853 + 921 WP_039674794.1 DUF808 domain-containing protein -
DQN65_RS07705 1689857..1690654 - 798 WP_039674792.1 zinc transporter ZupT -
DQN65_RS07710 1690780..1691598 + 819 WP_039674788.1 hypothetical protein -
DQN65_RS07715 1691847..1692101 + 255 WP_039674787.1 hypothetical protein -
DQN65_RS07720 1692111..1692410 - 300 WP_039674786.1 HigA family addiction module antidote protein Antitoxin
DQN65_RS07725 1692419..1692700 - 282 WP_082013920.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DQN65_RS07730 1693001..1694767 - 1767 WP_039674782.1 selenocysteine-specific translation elongation factor -
DQN65_RS07735 1694768..1696054 - 1287 WP_039674781.1 L-seryl-tRNA(Sec) selenium transferase -
DQN65_RS07745 1696206..1697180 + 975 WP_039674779.1 selenide, water dikinase SelD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(18-93)

Antitoxin

Toxin-antitoxin system, antidote protein, HigA

(1-97)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10797.29 Da        Isoelectric Point: 10.8344

>T292598 WP_082013920.1 NZ_LS483460:c1692700-1692419 [Corynebacterium minutissimum]
MIQSFANRDTELVWLRQASPRIDSRIHKTANRKLHQLDAAVSLQSLRVPPGNRLEALKGDRKGMYSIRVNQQWRITFRWT
EAGPADVAIEDYH

Download         Length: 282 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 11085.78 Da        Isoelectric Point: 6.2247

>AT292598 WP_039674786.1 NZ_LS483460:c1692410-1692111 [Corynebacterium minutissimum]
MSTKLYPPIHPGEVLNEDFIKAFGITQHKLAMAIGVPPRRINEIVHGKRGITADTALRLGRYFGVEPQFWVNLQGRYELE
IAEDSIAEEVSSIKPLEVA

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References