Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-MqsA
Location 1752374..1753007 Replicon chromosome
Accession NZ_LS483452
Organism Shewanella benthica strain DB21MT-2

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag SHEWBE_RS08100 Protein ID WP_112352236.1
Coordinates 1752675..1753007 (-) Length 111 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag SHEWBE_RS08095 Protein ID WP_112352235.1
Coordinates 1752374..1752688 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SHEWBE_RS20005 1749572..1749736 + 165 WP_172605666.1 hypothetical protein -
SHEWBE_RS08085 1749922..1751274 - 1353 WP_112352233.1 8-oxoguanine deaminase -
SHEWBE_RS08095 1752374..1752688 - 315 WP_112352235.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
SHEWBE_RS08100 1752675..1753007 - 333 WP_112352236.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
SHEWBE_RS08105 1753921..1754335 + 415 Protein_1507 tyrosine-type recombinase/integrase -
SHEWBE_RS08110 1754332..1755451 + 1120 Protein_1508 IS91 family transposase -
SHEWBE_RS08115 1755736..1755960 - 225 WP_112352237.1 hypothetical protein -
SHEWBE_RS08120 1756306..1756581 + 276 WP_112352238.1 tyrosine-type recombinase/integrase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(8-103)

Antitoxin

Antitoxin MqsA/HigA-2

(17-101)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 12918.89 Da        Isoelectric Point: 10.0278

>T292594 WP_112352236.1 NZ_LS483452:c1753007-1752675 [Shewanella benthica]
MKCIFVESRIFEKFRDNYLSDEEFRLFQAELMSNPKQGDVIQGTGGLRKVRVASKGKGKRGGSRVIYYFLDEKRRCYLLT
IYGKSEMSDLTADQKKQLKAFMEVWRNEQS

Download         Length: 333 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11785.38 Da        Isoelectric Point: 6.6453

>AT292594 WP_112352235.1 NZ_LS483452:c1752688-1752374 [Shewanella benthica]
MSNRDLFSELNSALVEAKEHSEGKLTLKTHLVNDVSELDISPNEIVNIREKFNMSRGVFARLLHTSSRTLENWEQGRSAP
NGQAITLLKLVQRHPEILTHIAEL

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References