Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yafN-yafO (relBE)/YafO-YafN
Location 345049..345734 Replicon chromosome
Accession NZ_LS483452
Organism Shewanella benthica strain DB21MT-2

Toxin (Protein)


Gene name yafO Uniprot ID -
Locus tag SHEWBE_RS01695 Protein ID WP_112351150.1
Coordinates 345339..345734 (+) Length 132 a.a.

Antitoxin (Protein)


Gene name yafN Uniprot ID -
Locus tag SHEWBE_RS01690 Protein ID WP_112351148.1
Coordinates 345049..345342 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SHEWBE_RS01665 340742..341140 + 399 WP_112351141.1 ribosome-associated heat shock protein Hsp15 -
SHEWBE_RS01670 341250..342113 + 864 WP_112351142.1 Hsp33 family molecular chaperone HslO -
SHEWBE_RS01675 342640..344181 + 1542 WP_112351144.1 phosphoenolpyruvate carboxykinase -
SHEWBE_RS01685 344645..344887 + 243 WP_112351146.1 helix-turn-helix transcriptional regulator -
SHEWBE_RS01690 345049..345342 + 294 WP_112351148.1 type I toxin-antitoxin system antitoxin YafN Antitoxin
SHEWBE_RS01695 345339..345734 + 396 WP_112351150.1 type II toxin-antitoxin system YafO family toxin Toxin
SHEWBE_RS01700 346143..347990 + 1848 WP_112351152.1 M14 family metallopeptidase -
SHEWBE_RS01705 348100..348399 - 300 WP_112351154.1 hypothetical protein -
SHEWBE_RS01710 348396..348998 - 603 WP_112351156.1 TonB-dependent receptor -
SHEWBE_RS01715 349012..349641 - 630 WP_172605626.1 TonB-dependent receptor plug domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin YafO

(27-129)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 132 a.a.        Molecular weight: 15069.18 Da        Isoelectric Point: 6.6928

>T292593 WP_112351150.1 NZ_LS483452:345339-345734 [Shewanella benthica]
VTRVFKARPILDALTEAEQHQLVSDFKSYKEGELPELFGRDVLYDHPMNLAAIKDEEVRHLHLGNADAPWPIWKAQFNRT
SDKHLVYCCGDTHPDRYLLMAILTPSAHDKAKDNNVMSRLGTMAEKFKEIH

Download         Length: 396 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10719.26 Da        Isoelectric Point: 4.5983

>AT292593 WP_112351148.1 NZ_LS483452:345049-345342 [Shewanella benthica]
MTVRLIYAEKIVSATEVRKGVNQYFIDEPVAVLSNNKPTGYMVGAALFERMILLIEKQSEGANSSFRPATARLQAMAFVS
EKSLLNATDDELGEFSE

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References