29259

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-MqsA
Location 1571616..1572249 Replicon chromosome
Accession NC_020802
Organism Psychromonas sp. CNPT3

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag PCNPT3_RS06925 Protein ID WP_015465160.1
Coordinates 1571917..1572249 (-) Length 111 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag PCNPT3_RS06920 Protein ID WP_015465159.1
Coordinates 1571616..1571930 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PCNPT3_RS06890 1567237..1568010 - 774 WP_015465154.1 hypothetical protein -
PCNPT3_RS06895 1568369..1569223 + 855 Protein_1333 IS110 family transposase -
PCNPT3_RS06900 1569262..1569792 - 531 WP_015465155.1 hypothetical protein -
PCNPT3_RS06905 1569892..1570140 - 249 WP_015465156.1 hypothetical protein -
PCNPT3_RS06910 1570353..1570976 - 624 WP_015465157.1 DUF2026 domain-containing protein -
PCNPT3_RS06920 1571616..1571930 - 315 WP_015465159.1 transcriptional regulator Antitoxin
PCNPT3_RS06925 1571917..1572249 - 333 WP_015465160.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PCNPT3_RS06930 1572553..1573659 - 1107 WP_015465161.1 hypothetical protein -
PCNPT3_RS06935 1573652..1574605 - 954 WP_015465162.1 hypothetical protein -
PCNPT3_RS06940 1575042..1575671 - 630 WP_015465163.1 pseudouridine synthase -
PCNPT3_RS06945 1575792..1577036 - 1245 WP_015465164.1 lipoprotein-releasing ABC transporter permease subunit LolE -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(9-105)

Antitoxin

Cro/C1-type helix-turn-helix domain

(48-94)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 12953.88 Da        Isoelectric Point: 9.9970

>T29259 WP_015465160.1 NC_020802:c1572249-1571917 [Psychromonas sp. CNPT3]
MRNVFVESKVFEKHRDNYLSDDEFRVFQTQLMANPAVGDVIQGTGGLRKVRVASKGKGKRGGARVIYYYFDIHFRFYLLT
IYAKNEMSDLTMDQKRQLKKFVEVWCNEQS

Download         Length: 333 bp

>T29259 NC_020802:c1572249-1571917 [Psychromonas sp. CNPT3]
ATGAGAAATGTATTTGTAGAATCGAAGGTTTTTGAAAAACATCGTGATAATTATTTGTCAGATGATGAGTTTAGAGTATT
TCAAACTCAATTAATGGCCAATCCTGCCGTTGGAGATGTTATTCAAGGCACAGGCGGTCTACGAAAAGTTAGAGTTGCTA
GTAAAGGGAAAGGAAAAAGGGGAGGGGCGCGAGTGATCTATTATTACTTTGATATACATTTTCGTTTTTACCTTTTAACC
ATTTACGCTAAAAATGAAATGTCTGACTTAACAATGGATCAAAAACGTCAATTGAAAAAGTTTGTGGAGGTATGGTGCAA
TGAACAATCGTGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11513.14 Da        Isoelectric Point: 9.9235

>AT29259 WP_015465159.1 NC_020802:c1571930-1571616 [Psychromonas sp. CNPT3]
MNNRDLFSELSSALVDAKNHSEGKLTLRTHKVALSSGLGISPVEIIGIREKFNLSRGVFAQLLHTSSRTLENWEQGRSAP
NGQAITLLKLVQRYPETLTQIAEL

Download         Length: 315 bp

>AT29259 NC_020802:c1571930-1571616 [Psychromonas sp. CNPT3]
ATGAACAATCGTGACTTGTTTTCAGAATTAAGCTCGGCGCTGGTTGATGCTAAAAATCACTCAGAAGGTAAATTAACTTT
ACGAACACATAAAGTTGCCTTAAGTAGTGGACTTGGAATTAGTCCCGTTGAAATTATTGGGATAAGAGAAAAATTTAACT
TATCTCGAGGTGTCTTCGCGCAGTTACTGCACACATCATCAAGGACATTAGAAAATTGGGAGCAAGGGCGTAGTGCACCA
AATGGTCAAGCAATAACGCTATTAAAATTAGTTCAGCGCTACCCTGAAACATTGACTCAAATAGCAGAGTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References