292524

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 294630..295143 Replicon chromosome
Accession NZ_LS483413
Organism Streptococcus dysgalactiae subsp. equisimilis strain NCTC7136

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag DQN40_RS01610 Protein ID WP_084916229.1
Coordinates 294630..294884 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag DQN40_RS01615 Protein ID WP_003053797.1
Coordinates 294877..295143 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQN40_RS01580 290872..291282 - 411 WP_003053802.1 conjugal transfer protein -
DQN40_RS01585 291285..291509 - 225 WP_003053785.1 hypothetical protein -
DQN40_RS01590 291513..292523 - 1011 WP_022554213.1 conjugal transfer protein -
DQN40_RS01595 292535..293071 - 537 WP_003053800.1 hypothetical protein -
DQN40_RS01600 293098..293328 - 231 WP_003053793.1 hypothetical protein -
DQN40_RS01605 293348..294574 - 1227 WP_084916231.1 replication initiation factor domain-containing protein -
DQN40_RS01610 294630..294884 - 255 WP_084916229.1 Txe/YoeB family addiction module toxin Toxin
DQN40_RS01615 294877..295143 - 267 WP_003053797.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
DQN40_RS01620 295408..297093 - 1686 WP_084916228.1 cell division protein FtsK -
DQN40_RS01625 297110..297571 - 462 WP_003056467.1 hypothetical protein -
DQN40_RS01630 297590..297886 - 297 WP_003056470.1 hypothetical protein -
DQN40_RS01635 297926..298171 - 246 WP_003056472.1 hypothetical protein -
DQN40_RS01640 298744..299085 + 342 WP_110408064.1 helix-turn-helix domain-containing protein -
DQN40_RS01645 299289..299594 + 306 WP_014612001.1 hypothetical protein -
DQN40_RS01650 299629..299988 - 360 WP_003053656.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 270073..327491 57418


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(4-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10502.78 Da        Isoelectric Point: 8.4060

>T292524 WP_084916229.1 NZ_LS483413:c294884-294630 [Streptococcus dysgalactiae subsp. equisimilis]
MFNFTEEAWEDYTSWQREDKKNLKRINRLIEDIKRHPFEGIGKPEPLKYRYSGAWSRRITDEHRLVYTVEQNDIYFLSFR
DHYK

Download         Length: 255 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10402.81 Da        Isoelectric Point: 4.5216

>AT292524 WP_003053797.1 NZ_LS483413:c295143-294877 [Streptococcus dysgalactiae subsp. equisimilis]
MEAVVYSNFRNNLKDYMKKVNDEYEPLMVVNKNPEENIVVLSKDNWDSIQETIRIMNNEYLSDKVLSGLEQVKQKKVTQH
QLLEVEDV

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References