Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2519657..2519841 Replicon chromosome
Accession NZ_LS483324
Organism Staphylococcus aureus strain NCTC10344

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag DQL79_RS13210 Protein ID WP_000482647.1
Coordinates 2519734..2519841 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2519657..2519717 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQL79_RS13185 2515111..2515278 - 168 WP_001790576.1 hypothetical protein -
DQL79_RS13195 2515509..2517242 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
DQL79_RS13200 2517267..2519030 - 1764 WP_001064814.1 ABC transporter ATP-binding protein/permease -
- 2519657..2519717 + 61 - - Antitoxin
DQL79_RS13210 2519734..2519841 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
DQL79_RS13215 2519975..2520361 - 387 WP_000779360.1 flippase GtxA -
DQL79_RS13220 2520619..2521761 + 1143 WP_001176863.1 glycerate kinase -
DQL79_RS13225 2521821..2522480 + 660 WP_000831298.1 membrane protein -
DQL79_RS13230 2522662..2523873 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
DQL79_RS13235 2523996..2524469 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T292371 WP_000482647.1 NZ_LS483324:c2519841-2519734 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT292371 NZ_LS483324:2519657-2519717 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References