Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2628728..2628912 Replicon chromosome
Accession NZ_LS483319
Organism Staphylococcus aureus strain NCTC13140

Toxin (Protein)


Gene name SprA2 Uniprot ID Q2FVI9
Locus tag DQL82_RS14045 Protein ID WP_000482650.1
Coordinates 2628805..2628912 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2628728..2628788 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQL82_RS14020 2624258..2624425 - 168 WP_001790576.1 hypothetical protein -
DQL82_RS14030 2624656..2626389 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
DQL82_RS14035 2626414..2628177 - 1764 WP_001064838.1 ABC transporter ATP-binding protein/permease -
- 2628728..2628788 + 61 - - Antitoxin
DQL82_RS14045 2628805..2628912 - 108 WP_000482650.1 type I toxin-antitoxin system Fst family toxin Toxin
DQL82_RS14050 2629046..2629432 - 387 WP_000779358.1 flippase GtxA -
DQL82_RS14055 2629700..2630842 + 1143 WP_001176863.1 glycerate kinase -
DQL82_RS14060 2630902..2631561 + 660 WP_111759485.1 hypothetical protein -
DQL82_RS14065 2631743..2632954 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
DQL82_RS14070 2633077..2633550 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T292356 WP_000482650.1 NZ_LS483319:c2628912-2628805 [Staphylococcus aureus]
MFNLLINIMTSAISGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT292356 NZ_LS483319:2628728-2628788 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2C9TTS8

Antitoxin

Download structure file

References