Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2337154..2337433 Replicon chromosome
Accession NZ_LS483319
Organism Staphylococcus aureus strain NCTC13140

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag DQL82_RS12445 Protein ID WP_001802298.1
Coordinates 2337329..2337433 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 2337154..2337333 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQL82_RS12425 2333353..2334018 - 666 WP_045177733.1 SDR family oxidoreductase -
DQL82_RS12430 2334170..2334490 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
DQL82_RS12435 2334492..2335472 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
DQL82_RS12440 2335738..2336829 + 1092 WP_000495671.1 lytic regulatory protein -
- 2337154..2337333 + 180 - - Antitoxin
DQL82_RS12445 2337329..2337433 - 105 WP_001802298.1 hypothetical protein Toxin
DQL82_RS15670 2337594..2338077 - 484 Protein_2304 recombinase family protein -
DQL82_RS12455 2338120..2339256 - 1137 WP_000115564.1 SAP domain-containing protein -
DQL82_RS12460 2339545..2339637 + 93 WP_001790138.1 hypothetical protein -
DQL82_RS12465 2340342..2341199 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
DQL82_RS12470 2341267..2342049 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T292351 WP_001802298.1 NZ_LS483319:c2337433-2337329 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 180 bp

>AT292351 NZ_LS483319:2337154-2337333 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTC
AAAGCGAATAGAAGGTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References