Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-SprF3/-
Location 2161361..2161660 Replicon chromosome
Accession NZ_LS483319
Organism Staphylococcus aureus strain NCTC13140

Toxin (Protein)


Gene name txpA Uniprot ID Q2FWU9
Locus tag DQL82_RS11420 Protein ID WP_011447039.1
Coordinates 2161484..2161660 (-) Length 59 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 2161361..2161416 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQL82_RS11375 2156696..2156956 + 261 WP_001791826.1 hypothetical protein -
DQL82_RS11380 2157009..2157359 - 351 WP_000702262.1 complement inhibitor SCIN-A -
DQL82_RS11385 2158040..2158489 + 450 WP_000727652.1 chemotaxis-inhibiting protein CHIPS -
DQL82_RS11390 2158584..2158919 - 336 Protein_2102 SH3 domain-containing protein -
DQL82_RS11400 2159569..2160060 - 492 WP_000919350.1 staphylokinase -
DQL82_RS11405 2160251..2161006 - 756 WP_000861038.1 CHAP domain-containing protein -
DQL82_RS11410 2161018..2161272 - 255 WP_000611512.1 phage holin -
DQL82_RS11415 2161324..2161431 + 108 WP_001791821.1 hypothetical protein -
- 2161353..2161492 + 140 NuclAT_0 - -
- 2161353..2161492 + 140 NuclAT_0 - -
- 2161353..2161492 + 140 NuclAT_0 - -
- 2161353..2161492 + 140 NuclAT_0 - -
- 2161361..2161416 + 56 - - Antitoxin
DQL82_RS11420 2161484..2161660 - 177 WP_011447039.1 putative holin-like toxin Toxin
DQL82_RS11425 2161810..2162106 - 297 WP_000539688.1 DUF2951 domain-containing protein -
DQL82_RS11430 2162164..2162451 - 288 WP_001040261.1 hypothetical protein -
DQL82_RS11435 2162498..2162650 - 153 WP_001153681.1 hypothetical protein -
DQL82_RS11440 2162640..2166425 - 3786 WP_000582158.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - scn / chp / sak / hlb / groEL 2157009..2214011 57002


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(30-58)


Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6849.45 Da        Isoelectric Point: 10.6777

>T292346 WP_011447039.1 NZ_LS483319:c2161660-2161484 [Staphylococcus aureus]
MDRWWLSEYKEVVPMVALLKSLERRRLMITISTMLQFGLFLIALIGLVIKLIELSNKK

Download         Length: 177 bp

Antitoxin


Download         Length: 56 bp

>AT292346 NZ_LS483319:2161361-2161416 [Staphylococcus aureus]
AAAAAGGGCAACATGCGCAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 7NS1

Antitoxin

Download structure file

References